Biggins, Sue

Faculty Profile

Submitted by Biggins, Sue on Fri, 10/08/2010 - 6:23pm

First Name:

Sue

Last Name:

Biggins

Title:

Member

Primary Institution:

FHCRC

Department/Division:

Basic Sciences

Department/Division:

other

E-Mail:

sbiggins@fhcrc.org

Mail/Box #:

A2-168

Office Location:

A2-155

Office Phone:

(206) 667-1351

Alternate Phone:

(206) 667-5766

Lab Website:

http://labs.fhcrc.org/biggins/

Research

Research Summary:

How do cells faithfully inherit a complete set of chromosomes during every cell division? We are studying the mechanisms that govern chromosome segregation during the cell cycle. Our focus is on the kinetochore, the protein complex that binds to microtubules. We study the regulation of kinetochore assembly and function, and the mechanisms that establish the specialized chromatin structure at centromeres. Recently, we have developed two ways to purify kinetochores and are now conducting biophysical and structural studies to complement the genetics and cell biology in the lab.

Short Research Description:

Regulation of Chromosome Segregation

Areas of Interest:

Gene Expression, Cell Cycle & Chromosome Biology

Keywords:

<p> Cell Biology, Genetics, Mitosis, Cell Cycle, Chromosomes, Genetics, Kinetochores, Yeast, Aurora kinase</p>

Publications

PubMed Search Term:

"Biggins S" [author] NOT renal

Taking Students

Year:

2012 - 2015

Search

Biggins, Sue

Faculty Profile

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