Tapscott, Stephen

Faculty Profile

First Name: 
Stephen
Last Name: 
Tapscott
[field_fname-formatted] [field_lname-formatted]
Title: 
Professor
Primary Institution: 
FHCRC
Department/Division: 
Human Biology
Department/Division: 
other
E-Mail: 
Mail/Box #: 

C3-168

Office Location: 

C3-023 FHCRC

Office Phone: 
(206) 667-4499
Research

Research Summary: 

The Tapscott lab focuses on gene transcription in a chromatin context in normal development and disease. The lab uses the myogenic transcription factor MyoD and the neurogenic transcription factor NeuroD2 to study how complex programs of gene expression unfold during cell differentiation. In addition, the lab studies gene expression in rhabdomysarcomas (cancers with characteristics of skeletal muscle), medulloblastomas, and human muscular dystrophies. Other areas of research in the lab include DNA methylation, the formation of palindromes in the human cancer genome, gene and cell therapies for muscular dystrophy, and the biology of triplet repeats and their associated diseases.

Short Research Description: 
Regulation of gene expression
Areas of Interest: 
Cancer Biology
Gene Expression, Cell Cycle & Chromosome Biology
Keywords: 
<p> cancer cell biology, cell biology, developmental biology, differentiation, gene regulation, growth and regeneration, neurobiology, neurology, neuromuscular diseases, molecular genetics, pathogenesis, signal transduction, stem cells</p>
Publications


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