Rosen Building, Room 362
We are currently focusing on the pathogenesis of HIV infection with particular emphasis on the mechanisms for controlling HIV-1 and SIV at low levels in vivo. We are devoting considerable effort toward identifying HIV-1 strains which are defective or attenuated, and human genes that protect against and/or control HIV-1 infection. We also have intense interest in defining the role of CD14+ monocytes in HIV-1 transmission as well as during the very early course of HIV-1 infection. In addition, we are involved in studies to define events of transmission, and modes of protection against SIV infection (using the SIV/macaque model). The above studies should assist in developing new therapeutic strategies and HIV-1 vaccine or strategies to enhance vaccine efficacy.
Copyright © 2003-2013 Molecular & Cellular Biology Program, University of Washington
Fred Hutchison Cancer Research Center | University of Washington
Institute for Systems Biology | Seattle Biomed