Medicinal Biochemistry I - Winter 2008

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Course Objective

The goals of this course are to build a strong knowledge base in the principles of biochemistry and cell biology, link the principles of biochemistry to cell physiology, relate the genetic basis of diseases and inborn errors of metabolism to biochemical defects in the cell, study interactions of selected drugs with biomolecules resulting in altered cellular metabolism and examine cellular processes that regulate cell communication and homeostasis.

Course Schedule

Lectures Monday, Wednesday, Friday
8:30 am - 9:20 am
HSB T435

Recitation Wednesday
10:30 am -11:20 am
HSB K069

Instructors

Dr. Carlos Enrique Catalano, Course Director
Room H172H
Phone: 206/685-2468
catalanc@u.washington.edu
Office Hours: Mondays (12:30 pm - 1:30 pm)

Rishi Sanyal, Course TA
Room H172L
Phone: 206/616-0541
rjsanyal@u.washington.edu
Office Hours: Wednesdays (12:30 pm - 1:30 pm) and Fridays (2:00 pm - 3:00 pm)

Textbook

Thomas M. Devlin (2006) Textbook of Biochemistry, with Clinical Correlations, 6th edition, Wiley-Liss.

Course Calendar

Medicinal Biochemistry ­ Winter Quarter, 2008
Week Lecture # Date
1 1 January 7 Course Introduction; Cells and Chemistry
2 January 9 Amino Acids and Protein Structure
2 January 11 Protein Structure/Function - Myoglobin and Hemoglobin
2 3 January 14 Protein Structure/Function - Plasma Proteins
4 January 16 Protein Structure/Function - Collagen and the ECM
5 January 18 Protein Structure/Function - Catalysis and Enzymes
3 January 21 Academic Holiday - Happy MLK Day
6 January 23 Exam 1 (lectures 1-6)
7 January 25 Protein Structure/Function - Enzymes and Co-Enzymes
4 8 January 28 Protein Structure/Function - Enzymes and Co-Enzymes
9 January 30 Protein Structure/Function - Enzyme Kinetics
February 1 Protein Structure/Function - Enzyme Kinetics
5 10 February 4 Flow of Genetic Information, DNA Structure
11 February 6 DNA Replication and Repair
12 February 8 DNA Replication and Repair
6 13 February 11 DNA Replication and Repair
14 February 13 RNA Structure and Transduction
15 February 15 Exam 2 (lectures 7-14)
7 16 February 18 Academic Holiday - Happy Presidents Day
17 February 20 Regulation of Transcription - Prokaryotic cells
February 22 Regulation of Transcription - Prokaryotic cells
8 February 25 Protein Synthesis
18 February 27 Protein Synthesis, Folding
19 February 29 Lipids and Biological Membranes
9 20 March 3 Exam 3 (lectures 15-19)
21 March 5 Protein Processing, Targeting, Turnover
22 March 7 Biological Membranes and Membrane Transport
10 23 March 10 Membrane Transport and Signal Transduction
24 March 12 Signal Transduction
25 March 14 Cell Cycle, Cell Growth and Apotosis

Click here for complete syllabus (PDF)


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This page last updated: January 17, 2008