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Department of Medicinal Chemistry Faculty ATKINS, WILLIAM MARK (b. 1958) Professor, B.S., 1980, College of William & Mary; M.S., 1983, Harvard University; Ph.D., 1988, University of Illinois; Postdoctoral Fellow, Pennsylvania State University, 1988-1991. Protein engineering and site-directed mutagenesis as probes of enzyme mechanism and regulation; Fluorescence spectroscopy and high-pressure techniques to study subunit-subunit interactions in oligomeric proteins. (206) 685-0379. CATALANO, CARLOS ENRIQUE Professor, Pharm.D., 1983; Ph.D., 1987, University of California at San Francisco (206) 685-2468. ELMER, GARY WELLS (b. 1941) Professor, B.S., 1963; M.S., 1966; University of Connecticut; Ph.D., 1970, Rutgers University. Studies on drug metabolism by the intestinal microflora. Etiology and treatment of antibiotic associated diarrhea and colitis. Applications and mechanisms of biotherapeutic agents in infectious diseases. Drug interactions with herbal products. (206) 543-2055. GOODLETT, DAVID ROBINSON Associate Professor, B.S., 1982; M.S., 1988, Auburn University, Alabama; Ph.D., 1991, North Carolina State University. Proteomics method developoment in separation science and mass spectrometry applied to microbiology, prostate cancer, pediatric medulloblastomas. (206) 616-4586. HOWALD, WILLIAM NEAL (b. 1941) Research Scientist-Lecturer, Manager, School of Pharmacy Mass Spectrometry Facility, B.S., 1967, University of Washington, Chemistry. Application of mass spectrometric techniques to studies in the life sciences; development of analytical methodologies in support of these studies. (206) 543-6439. KUNZE, KENT LUVERN (b. 1952) Associate Professor, B.S. 1977, University of Washington; Ph.D., 1981, University of California at San Francisco. Development and use of Isozyme Specific Mechanism-based Inhibitors of Cytochrome P450 and the Application of in vitro Enzyme Kinetics to the Prediction of in vivo Drug Interactions in Man. (206) 685-3543. NELSON, SIDNEY DONALD (b. 1945) Professor and Dean School of Pharmacy , B.S., 1968, University of Washington; Ph.D., 1974, University of California, San Francisco; 1974-77, Pharmacology Research Associate, Laboratory of Chemical Pharmacology, NIH, Bethesda, Maryland. Drug metabolism as it relates to reactive intermediates and drug toxicity; deuterium isotope effects in drug action and metabolism; mass spectrometry, synthesis of enzyme inhibitors. (206) 543-1419. NELSON, WENDEL LANE (b. 1939) Professor, B.S., 1962, Idaho State University; Ph.D., 1965, University of Kansas. Conformational, configurational and mechanistic aspects of drug action and drug metabolism; stereo- and enantioselectivity of oxidative metabolic processes; selective ligands for opioid receptor subclasses. (206) 543-2209. RETTIE, ALLAN EDWARD (b. 1957) Professor and Chairman, B.Sc., 1979, Heriot-Watt University, Scotland; Ph.D., 1983, University of Newcastle-upon-Tyne, England; Postdoctoral Fellow, University of Washington, USA, 1984-87. Enzymology of oxidative drug metabolism: Flavin-containing monooxygenases and cytochrome P-450 in human tissues. (206) 685-0615. TOTAH, RHEEM, Asst. Professor (206) 543-9481. TRAGER, WILLIAM FRANK (b. 1937) Professor
Emeritus, B.S., 1960, University of San Francisco; Ph.D., 1965, University
of Washington; NIH Fellow, 1965, Chelsea College of Science and Technology,
London, England; Postdoctoral Fellow, 1967, University of Washington.
Drug metabolism; mechanisms of biotransformation; synthetic labeling with
stable and radioactive isotopes; mass spectrometry. Adjunct & Affiliate Faculty
Research Associates
Faculty and Research Openings Currently Available |
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