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Reminder: Check back here for dates, times, and locations for Winter 2009 Monday Night Meeting.

Monday Night Meeting Schedule

Winter 2008

Date Speaker Paper (Click title to download PDF) Abstract of Discussion
TBA TBA TBA TBA

 

Autumn 2008

Then and Now

Sometimes an idea will revolutionize scientific perceptions in a given field. Maybe the idea was right, or maybe it turned out to be a misconception. Either way, a select group of papers have changed thinking in science more so than the vast majority. Monday Night Meeting this quarter (autumn 2008) will attempt to examine a few of these. Our format this quarter will focus less on the precise investigation of one individual paper, and instead examine the central idea presented within, and trace its impact on the field for which it was written. Some of the questions we will attempt to answer include the central concept and results of the chosen paper, the impact it had at the time, and how it has changed what has gone both before and after. The paper may have turned out to be right or wrong, but looking at in the context of history is really the only way to know…
Date Speaker Paper (Click title to download PDF) Abstract of Discussion
10/20/08 Matthew Honaker Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates
in a Cytochrome P450 Active Site		 TBA
10/27/08 Elizabeth Medina Protein Fusion: A Novel Reaction in Bacteriophage λ Head Assembly TBA
11/03/08 Oliver Parkinson Pharmacogenetics of the S-Oxidation of S-Carboxymethyl-L-Cysteine TBA
11/10/08 Kelsey Hanson Cytochrome P-455 Complex Formation in the Metabolism of Phenylalkylamines-IV TBA
11/17/08 Pragya Singh An Approach to Correlate Tandem Mass Spectral Data of Peptides with Amino Acid Sequences in a Protein Database TBA
12/1/08 Peter Rademacher Drug Metabolism as a Cause of Drug Toxicity TBA

 

Spring 2008

Date Speaker Paper (Click title to download PDF) Abstract of Discussion
4/14/08 Peter Rademacher In Vitro Metabolism of a Model Cyclopropylamine to Reactive Intermediate: Insights into Trovafloxacin-Induced Hepatotoxicity Click here for Peter's questions
4/21/08 Tasha Downing Cytosolic Region of TM6 in P-Glycoprotein: Topographical Analysis and Functional Perturbation by Site Directed Labeling Click here for Tasha's questions
4/28/08 Caleb Woods What is the Active Species of Cytochrome P450 during Camphor Hydroxylation? QM/MM Studies of Different Electronic States of Compound I and of Reduced and Oxidized Iron-Oxo Intermediates

Caleb's questions TBA

Click here for Supporting Information
5/5/08 Mimi Nguyen

POSTPONED

Metabolic Activation of the Antitumor Drug
5-(Aziridin-1-yl)-2,4-Dinitrobenzamide (CB1954) by NO Synthases

 TBA
5/12/08 Rishi Sanyal Kemp elimination catalysts by computational enzyme design TBA
5/19/08 Tricia Zhao Heteromeric Complex Formation between CYP2E1 and CYP1A2: Evidence for the Involvement of Electrostatic Interactions Click here for Tricia's questions
5/26/08 HOLIDAY    

Wednesday

5/28/08

 Mimi Nguyen

RESCHEDULED

Metabolic Activation of the Antitumor Drug
5-(Aziridin-1-yl)-2,4-Dinitrobenzamide (CB1954) by NO Synthases

 TBA
6/2/08 Kip Conner, Kayte Zumberge & Michelle Leibrand Rotation talks  

 

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This page last updated: October 16, 2008