Meets Mondays from 4:00 - 5:00 PM in H-074.
NOTE: Email your papers in advance to Caryl Lynch for posting to the web site.

Monday Night Meeting (MedCh 582)
Schedule

Autumn 2009

Date Speaker Paper (Click title to download PDF) Questions for Discussion
10/05/09 No MNM No meeting  
10/12/09 Matt Honaker Exploring the Electron Transfer Properties of Neuronal Nitric-oxide Synthase by Reversal of the FMN Redox Potential (PDF) Supplemental Discussion (PDF)
10/19/09 Kelsey Hanson Effect of Intestinal Glucuronidation in Limiting Hepatic Exposure and Bioactivation of Raloxifene in Humans and Rats (PDF)  
10/26/09 Brendan Stamper The Mitochondrial Superoxide/Thioredoxin-2/Ask1 Signaling Pathway is Critically Involved in Troglitazone-Induced Cell Injury to Human Hepatocytes (PDF)  
11/2/09 Oliver Parkinson Simultaneous Expression of Plural Forms of Human Cytochrome P450 at Desired Ratios in HepG2 Cells: Adenovirus- mediated Tool for Cytochrome P450 Reconstitution (PDF)  
11/9/09 Peter Rademacher Selective Oxidation of Carbolide C-H Bonds by an Engineered Macrolide P450 Mono-oxygenase (PDF) Supporting Information (PDF)
11/16/09 Kayte Zumberge    
11/23/09 No MNM No meeting  
11/30/09 Pragya Singh    
12/7/09 Elizabeth Medina    

 

Spring 2009

Date Speaker Paper (Click title to download PDF) Questions for Discussion
03/30/09 Caleb Woods Kinetic Isotope Effects in Hydroxylation Reactions Effected by Cytochrome P450 Compounds I Implicate Multiple Electrophilic Oxidants for P450-Catalyzed Oxidations Caleb's Questions (DOC) or (PDF)
04/06/09 Kayte Zumberge Irreversible Inhibition of the Myobacterium tuberculosis β-Lactamase by Clavulanate  
04/13/09 Michelle Wahlin Dehydrogenation of Indoline by Cytochrome P450 Enzymes: A Novel "Aromatase" Process  
04/20/09 Rishi Sanyal Liver-Targeted Prodrugs of 2‘-C- Methyladenosine for Therapy of Hepatitis C Virus Infection  
04/27/09 Trisha Zhao Biotransformation of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin- 4(3H)-one (TZB-30878), a Novel 5-Hydroxytryptamine (5-HT)1A Agonist/5-HT3 Antagonist, in Human Hepatic Cytochrome P450 Enzymes  
05/04/09 Kip Conner In Vitro Metabolism and Covalent Binding of Enol-Carboxamide Derivatives and Anti-Inflammatory Agents Sudoxicam and Meloxicam: Insights into the Hepatotoxicity of Sudoxicam  
05/11/09 Mimi Nguyen Potent and Highly Selective Hypoxia-Activated Achiral Phosphoramidate Mustards as Anticancer Drugs  
05/18/09 Laura Shireman Cancelled  
05/25/09 HOLIDAY    
06/01/09 Rotation Talks (John Chapman, Jon Katayama, Eri Nakatani) TBA  

 

Winter 2009

Date Speaker Paper (Click title to download PDF)
01/12/09 No MNM  
01/19/09 HOLIDAY  
01/26/09 Brooke Vandenbrink Mode of Inhibition of ß-Hydroxydecanoyl Thioester Dehydrase by 3-Decynoyl-N-acetylcysteamine
02/02/09 Brendan Stamper The Fate of Acetanilide in Man
02/09/09 Tasha Ritchie Structure of the Multidrug Resistance P-glycoprotein to 2.5 nm Resolution Determined by Electron Microscopy and Image Analysis
02/16/09 HOLIDAY  
02/23/09 Shawna Hengel A Putative Role for Nicotinamide Adenine Dinucleotide-promoted Nuclear Protein Modification in the Antitumor Activity of N-Methyl-N-nitrosourea
03/02/09 Clara Hsia Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage
03/09/09 Mariko Nakano Expression and enzymatic activity of recombinant cytochrome P450 17α-hydroxylase in Escherichia coli
03/16-20 EXAMS WEEK  

 

 

Past Monday Night Meetings

 



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