Current literature papers discussed on Monday nights at 4:00pm in Room H-074 in the Health Sciences Building.
Past Monday Night Meetings
Autumn 2008
Then and Now
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Sometimes an idea will revolutionize scientific perceptions in a given field. Maybe
the idea was right, or maybe it turned out to be a misconception. Either way, a
select group of papers have changed thinking in science more so than the vast majority.
Monday Night Meeting this quarter (autumn 2008) will attempt to examine a few of
these. Our format this quarter will focus less on the precise investigation of
one individual paper, and instead examine the central idea presented within, and
trace its impact on the field for which it was written. Some of the questions we
will attempt to answer include the central concept and results of the chosen paper,
the impact it had at the time, and how it has changed what has gone both before
and after. The paper may have turned out to be right or wrong, but looking at in
the context of history is really the only way to know… |
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| Date | Speaker | Paper (Click title to download PDF) | |
| 10/20/08 | Matthew Honaker | Activation of CYP3A4: Evidence
for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site |
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| 10/27/08 | Elizabeth Medina | Protein Fusion: A Novel Reaction in Bacteriophage λ Head Assembly | |
| 11/03/08 | Oliver Parkinson | Pharmacogenetics of the S-Oxidation of S-Carboxymethyl-L-Cysteine | |
| 11/10/08 | Kelsey Hanson | Cytochrome P-455 Complex Formation in the Metabolism of Phenylalkylamines-IV | |
| 11/17/08 | Pragya Singh | An Approach to Correlate Tandem Mass Spectral Data of Peptides with Amino Acid Sequences in a Protein Database | |
| 12/1/08 | Peter Rademacher | Drug Metabolism as a Cause of Drug Toxicity | |
Spring 2008
Winter 2008
Autumn 2007
Spring 2007
| Date | Speaker | Paper (Click title to download PDF) | Discussion Questions (DOC format) |
| 4/16 | Wendel Nelson | No paper - topic is 'What a journal editor does and does not do" | Your questions are expected |
| 4/23 | Carrie Mosher | Metabolism-Dependent Mutagenicity of a Compound Containing a Piperazinyl Indazole Motif: Role of a Novel P450-Mediated Metabolic Reaction Involving a Putative Oxaziridine Intermediate | Click here for Carrie's discussion questions |
| 4/30 | Mariko Nakano | Metabolism of Furans in Vitro: Ipomeanine and 4-Ipomeanol | Click here for Mariko's discussion questions |
| 5/7 | Pragya Singh |
Covalent Modification of Microsomal Lipids by Thiobenzamide Metabolites in Vivo |
Click here for Pragya's discussion questions |
| 5/14 | Rishi Sanyal and Caleb Woods | Rotation talks | |
| 5/21 | Tricia Zhao & Mimi Nguyen | Rotation talks |
Winter 2007
Autumn 2006
Spring 2006
Winter 2006
Autumn 2005
Spring 2005
| Speaker | Paper |
| Sumit Mahajan | Direct Observation of Ligand Binding to Membrane Proteins in Living Cells by a Saturation Transfer Double Difference (STDD) NMR Spectroscopy Method Shows a Significantly Higher Affinity of Integrin alphaIIbbeta3 in Native Platelets than in Liposomes |
| John Harrelson | Kinetic Analysis of Oxidation of Coumarins by Human Cytochrome P450 2A6 |
| Rotation Talks |
Winter 2005
| Date | Speaker | Paper |
| Jan 24 | Carrie Mosher | Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentationImproved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation |
| Jan 31 | Josh Pearson | Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips |
| Feb 7 | Clara Hsia | Proteomic characterization of the human centrosome by protein correlation profiling |
| Feb 14 | Dustin Smith | Discovering potent and selective reversible inhibitors of enzymes in complex proteins |
| Feb 21 | HOLIDAY | |
| Feb 28 | Elva Gao | A Top-down method for the determination of residue-specific solvent accessibility in proteins |
| Mar 7 | Kevin Coe | Androgen receptor phosphorylation: regulation and identification of the phosphorylation sites |
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This page last updated: December 16, 2008