Dr. Browning's research is focused on the development of statistical and computational methods for analysis of large-scale genetic data from microarray genotyping and next-generation sequencing. These genetic data sets present computational and analytical challenges due to their size, and due to the complex patterns of inter-marker correlation in the data. Carefully engineered algorithms and software are necessary to extract the full information from these rich data sets.
Beagle - genotype imputation, haplotypic testing, haplotype phase inference, and identity-by-descent segment detection for unrelated individuals and parent-offspring trios.
Beagle Utilities - a collection of utility programs for manipulating large data files.
IBDseq - identity-by-descent segment detection for whole-genome sequence data.
SEQERR - genotype error rate estimation for whole-genome sequence data.
A complete list of my software is available on my faculty website.