R. Scott Hansen, Ph.D.

Emeritus Research Associate Professor, Medical Genetics

University of Washington
J-237 Health Sciences Building
Medical Genetics, Box 357360
Seattle, WA 98195-7360

Phone: (206) 543-4184
Phone: (206) 543-1619
FAX: (206) 543-0754
E-mail: supreme@uw.edu

Research Program:

see Stanley M. Gartler, Ph.D.

Representative Publications:

Hansen RS, Canfield TK, Lamb MM, Gartler SM, Laird CD: Association of fragile X syndrome with delayed replication of the FMR1 gene. Cell 73:1403-1409, 1993

Hansen RS, Canfield TK, Gartler SM: Unusual replication timing for the XIST gene in human fibroblasts. Hum Mol Genet: 4:813-820, 1995

Kawame H, Gartler SM, Hansen RS: Allele-specific replication timing in imprinted domains: Absence of asynchrony at several loci. Hum Mol Genet 4:2287-2293, 1995

Hansen RS, Canfield TK, Fjeld AD, Gartler SM: Role of late replication timing in the silencing of X-linked genes. Hum Mol Genet 5:1345-1353, 1996

Hansen RS, Canfield TK, Fjeld AD, Munn S, Laird CD, Gartler SM: A variable domain of delayed replication of FRAXA fragile X chromosomes: X inactivation-like spread of late replication. Proc Natl Acad Sci USA 94:4587-4592, 1997

Litt MD, Hansen RS, Hornstra IK, Gartler SM, Yang TP: 5-Azadeoxycytidine induced chromatin remodeling of the inactive X-linked HPRT gene promoter occurs prior to transcription factor binding and gene reactivation. J Biol Chem 272:14921-14926, 1997

Hansen RS, Canfield TK, Stanek AM, Keitges EA, Gartler SM: Reactivation of XIST in normal fibroblasts and a somatic cell hybrids: Abnormal localization of XIST RNA in hybrid cells. Proc Natl Acad Sci USA 95:5133-5138, 1998