David W. Emery, Ph.D.
Research Associate Professor of Medicine
K-236F Health Sciences Building
Medical Genetics, Box 357720
Phone: 206-616-4525, 206-543-2369
FAX: 206-543-3050
E-mail: demery@u.washington.edu
Research Profile (Community of Science)
Dr. Emery’s general research interests focus on the field of hematopoietic
stem cell gene therapy. This includes a broad interest in the mechanisms
of gene regulation and the transplantation biology of hematopoietic stem
cells. Past studies include the manipulation of transplantation immunity
in mice and miniature swine using retrovirus vectors for major histocompatibility
genes, and the enhancement of hematopoietic stem cell transplantation
across xenogeneic barriers. Current studies have focused on: 1) systematic
comparison of various nonhuman primates as pre-clinical large animal models
for hematopoietic stem cell gene therapy research; 2) development
and testing of retrovirus vectors for human hemoglobin genes in transplanted
mice; and 3) investigation of chromatin insulators for minimizing
negative position effects on retrovirus vector expression. Dr. Emery is
also the director of the clinical Gene and Cell Therapy Core Laboratory
under construction at the University of Washington’s General Clinical
Research Center. This core laboratory will support ongoing and future
clinical trials at the University of Washington Medical Center and affiliated
hospitals that require the genetic modification and/or ex vivo manipulation
of patient tissues under strict clinical standards.
©2003 Division of Medical Genetics,
University of Washington.
All rights reserved.
Design by Jessie Good
Last updated: January 2, 2004
