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R. Scott Hansen, Ph.D.Research Associate Professor, Medical Genetics Research Program:Representative Publications: Hansen RS, Canfield TK, Lamb MM, Gartler SM, Laird CD: Association of fragile X syndrome with delayed replication of the FMR1 gene. Cell 73:1403-1409, 1993 Hansen RS, Canfield TK, Gartler SM: Unusual replication timing for the XIST gene in human fibroblasts. Hum Mol Genet: 4:813-820, 1995 Kawame H, Gartler SM, Hansen RS: Allele-specific replication timing in imprinted domains: Absence of asynchrony at several loci. Hum Mol Genet 4:2287-2293, 1995 Hansen RS, Canfield TK, Fjeld AD, Gartler SM: Role of late replication timing in the silencing of X-linked genes. Hum Mol Genet 5:1345-1353, 1996 Hansen RS, Canfield TK, Fjeld AD, Munn S, Laird CD, Gartler SM: A variable domain of delayed replication of FRAXA fragile X chromosomes: X inactivation-like spread of late replication. Proc Natl Acad Sci USA 94:4587-4592, 1997 Litt MD, Hansen RS, Hornstra IK, Gartler SM, Yang TP: 5-Azadeoxycytidine induced chromatin remodeling of the inactive X-linked HPRT gene promoter occurs prior to transcription factor binding and gene reactivation. J Biol Chem 272:14921-14926, 1997 Hansen RS, Canfield TK, Stanek AM, Keitges EA, Gartler SM: Reactivation of XIST in normal fibroblasts and a somatic cell hybrids: Abnormal localization of XIST RNA in hybrid cells. Proc Natl Acad Sci USA 95:5133-5138, 1998
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©2003 Division
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