Medical Genetics clinical staff profiles

LOUANNE HUDGINS, M.D.

Assistant Professor of Medicine
K-236B Health Sciences Building
Medical Genetics, Box 357720
Phone: 206-616-4566, 206-616-4567
FAX: 206-616-7288
E-mail: horwitz@u.washington.edu

Research Program:

The primary interest of Dr. Hudgins is in the clinical delineation of malformation syndromes, especially those involving limb malformations. This is made possible through her involvement in the Regional Genetics Clinics at Children’s Hospital & Medical Center as well as those at other sites in Washington state. She also is the Director of the State of Alaska Genetics & Birth Defects Clinics. Her interest in limb malformations has led to collaboration with a number of molecular researchers. Her studies aim to better delineate the clinical spectrum and inheritance patterns of some of the syndromes in which limb malformations are seen and to investigate the molecular basis of limb development.

Investigator: Dr. Hudgins is an Associate Professor of Pediatrics and Adjunct Associate Professor of Medicine (Medical Genetics).

Representative Publications:

Hudgins L, Cassidy SB: Hand and foot length in Prader-Willi syndrome. Am J Med Genet 41:5-9, 1991

Hudgins L, Rosengren S, Treem W, Hyams J: Early cirrhosis in survivors with Jeune throacis dystrophy. J Pediatr 120:754-756, 1992

McCall CP, Hudgins L, Cloutier M, Greenstein RM, Cassidy SB: Jarcho-Levin syndrome: Unusual survival in a classical case. Am J Med Genet 49:328-332, 1994

Erickson RP, Hudgins L, Stone JF, Schmidt S, Wilkie C, Glover TW: A "balanced" Y;16 translocation associated with Turner-like neonatal lymphedema suggests the location of a potential anti-Turner gene on the Y chromosome. Cytogenet and Cell Genet 71:163-167, 1995

Crackower MA, Scherer SW, Rommens JM, Hui C-C, Poorkaj P, Soder S, Cobben JM, Buys C, Hudgins L, Evans JP, Tsui L-C: Characterization of the split hand/split foot malformation locus SHFM1 at 7q21.3-q22.1 and analysis of a candidate gene for its expression during limb development. Hum Mol Genet 5:571-599, 1996

Kawame H, Pagon RA, Hudgins L: Digital anomalies, microcephaly and normal intelligence: New syndrome or Feingold syndrome? Am J Med Genet 69:240-244, 1997

Greally MT, Carey JC, Milewicz DM, Hudgins L, Goldberg RB, Shprintzen RJ, Cousineau AJ, Smith WL, Judisch GF, Hanson JW: Shprintzen-Goldberg syndrome: A clinical analysis. Am J Med Genet 76: 202-212, 1998

Hudgins L, Geer JS, Cassidy SB: Phenotypic differences in African-Americans with Prader-Willi syndrome. Genetics in Medicine 1: 14-51, 1998

Dinulos MB, Sternen DL, Graham CB, Hudgins L: Expansile bone lesions in a three generation family. Am J Med Genet 82: 1-5, 1999

Kawame H, Hannibal MC, Hudgins L, Pagon RA: Phenotypic spectrum and management issues in Kabuki syndrome. J Pediatr (in press)

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