A. Dusty Miller, Ph.D.
Member of Fred Hutchinson Cancer Research Center
Affiliate Professor of Pathology
FHCRC, Box 358080
1100 Fairview Ave N, Room C2-105
Seattle, WA 98109-1024
Phone: 206-667-2890, 206-667-2855
FAX: 206-667-6523
E-mail: dmiller@fhcrc.org
Research: Advances in molecular biology have made it feasible to cure genetic disease by transfer of corrective genes to somatic tissues of humans. Dr. Miller has focused on the development of viral vectors derived from retroviruses and adeno-associated virus, and has demonstrated gene transfer and expression in many somatic cell types in culture and in animals. These vectors have been used in many gene transfer trials in humans, but much development work remains to make gene therapy an effective treatment. Other ongoing studies focus on the basic biology and properties of adeno-associated virus vectors and their potential for use in gene therapy, and on retrovirus biology, including the nature of the receptors used for entry of retroviruses into cells and the evolution of the retrovirus envelope proteins that interact with these receptors.
Investigator: Dr. Miller is a Member of the Divisions
of Human Biology and Basic Sciences of the Fred Hutchinson Cancer Research
Center. He is an Affiliate Professor of Pathology at the University of
Washington.
©2003 Division
of Medical Genetics, University of Washington.
All rights reserved.
Design by Jessie Good
Last updated: April 29, 2003
