Gail Jarvik, head of the Division of Medical Genetics, is PI of a new grant to develop techniques for translating the products of gene sequencing into patient care. The National Human Genome Research Institute (NHGRI) and the National Cancer Institute will provide the UW project with $2.3 million for each of 4 years. The project is part of a broad initiative by the NHGRI to carry forward the knowledge acquired through the monumental Human Genome Project and advance its application to clinical medicine. The $416 million effort includes further support of three existing Large-Scale Genome Sequencing Centers. In addition, three Mendelian Disorders Genome Centers will be funded, including the UW Center for Mendelian Genomics (PIs Deborah Nickerson, Michael Bamshad, Mark Rieder, and Jay Shendure), which was awarded $5.2 million per year for 4 years.
Dr. Jarvik's project is one of five Clinical Sequencing Exploratory Research Projects that will investigate ways to incorporate genomic data into medical practice and address related ethical and social issues. Others involved include DOM members Fuki Hisama, Robin Bennett, Arno Motulsky, Wendy Raskind, Virginia Sybert, and Peter Byers, as well as Wylie Burke (Bioethics), S. Malia Fullerton (Bioethics), David Veenstra (Pharm), and Mark Rieder (Gen Sci). Other projects are funded at Baylor, Brigham and Women's, Children's Philadelphia, and the University of North Carolina.
Dr. Jarvik holds the Arno G. Motulsky Endowed Chair in Medicine and is founding head of the Northwest Institute for Genetic Medicine. She said of the project, "This is very exciting because we will actually be piloting using sequencing of the entire coding regions of the genome on UW Medicine patients. We will use a randomized controlled design to look at the health care outcomes of this promising new technology. I would like to point out that of the five clinical sequencing awards, three of the lead investigators were UW Medical Genetics fellows - Jim Evans [UNC], Sharon Plon [Baylor], and myself. Now that is an impact on training the next generation!"
The 3rd Annual Arno & Gretel Motulsky lecture was held on Wednesday July 27th 2011; our speaker was genetics pioneer and Nobel Laureate James D. Watson. Dr. Watson, together with the late Francis Crick, discovered the structure of DNA in 1953 and, with Crick and Maurice Wilkins, received the 1962 Nobel Prize in Physiology or Medicine. Today he is chancellor emeritus of the Cold Spring Harbor Laboratory. The lecture honors Emeritus Professor Arno G. Motulsky, founder of the Division of Medical Genetics, and the late Mrs. Motulsky.
Dr. Maynard Olson, Professor Emeritus of Medicine and Genome Sciences, honored the career
of Dr. Stan Gartler on January 28th 2011. Click here to download the lecture.
Click here to download this video.
The Division of Medical Genetics is pleased to announce that Fuki M. Hisama, M.D., has become the new Program Director of the Medical Genetics Residency Program, effective January 1st 2011. Dr. Hisama, Associate Professor of Medicine (Medical Genetics), joined the faculty in July of 2009 and serves as the Medical Director for the UWMC Medical Genetics Clinic. She succeeds Peter H. Byers, M.D., who has served as Program Director since 1997. Peter will continue to supervise the ABMG accredited Clinical Cytogenetics, Clinical Molecular, and Clinical Biochemical training programs while the clinical program transitions.
We extend our sincere appreciation to Peter for his service to the Medical Genetics Residency Program. Under his watch the program evolved to an ACGME accredited Residency. We have trained fellows and residents who are successfully engaged in academic medicine throughout the country. Peter's leadership has been integral to the success of our training programs and the evolution of the Clinical Medical Genetics Residency and the selection and training of outstanding graduates. Thank you!
Mary-Claire King, the American Cancer Society Professor of Medicine and Genome Sciences, was honored in New York last month by Cold Spring Harbor Laboratory which presented her with a Double Helix Medal. The medal recognizes exceptional individuals who have dedicated their lives to raising awareness of the importance of genetic research for improving human health.
King was the first to prove that breast cancer is inherited in some families, as the result of mutations in the gene that she named BRCA1. Read more...
Dr. Mary-Claire King, the American Cancer Society Professor of Medicine and Genome Sciences, has been named president-elect of the American Society of Human Genetics and will become president in January 2012.
Look for: Is Cancer Hiding in Your Family History? - Part 1 & 2
featuring Dr. Mary Claire King, Dr. Teresa Brentnall, and Robin Bennett. view them online today.