David Baker to Give Science in Medicine Lecture
David Baker, an associate professor of biochemistry, will present the Science in Medicine Lecture titled "Prediction and Design of Macromolecular Structures, Interactions, and Functions" at noon, Thursday, March 3 in Hogness Auditorium at the UW Health Sciences Center in Seattle. The lecture will also be simultaneously televised at Harborview Medical Center in the Research and Training Building in room 121 and VA Puget Sound Health Care System in Building 1 in room 518.
Baker and his colleagues consistently have been ranked the best in the world at interpreting amino acid sequences and predicting their 3-D structures. One of their greatest achievements is the development of Top7, the first globular protein designed from scratch, contained a new fold, and was validated by its X-ray crystal structure. Top7 was designed and synthesized using protein design-sequence algorithms and the group's structure-prediction program, Rosetta.
Baker received his B.A. at Harvard University, his Ph.D. at the University of California, Berkeley, and carried out his postdoctoral work at UC, San Francisco, before joining the faculty at the UW in 1994. He is also an adjunct professor in genome sciences, bioengineering, and physics, and an assistant investigator for the Howard Hughes Medical Institute.
He has also received young investigator awards from the National Science Foundation, Packard Foundation, Beckman Foundation, Protein Society and the International Society for Computational Biology, as well as a Foresight Institute Feynman Prize in Nanotechnology.