Skip to Content

Trikudanathan Subbulaxmi (4)

Subbulaxmi Trikudanathan, MD, MRCP, MMSc

Metabolism, Endocrinology and Nutrition

Clinical Assistant Professor of Medicine


Dr. Subbu Trikudanathan specializes in Endocrinology with particular focus on diabetes, polycystic ovarian syndrome, adrenal disorders, thyroid disorders and metabolic bone disease.


Dr. Subbulaxmi Trikudanathan received her medical degree from Madras Medical College in India. She completed residency and endocrine fellowship training at University College of London, United Kingdom. Subsequently she moved to Children’s Hospital Boston, Harvard Medical School to conduct research in costimulatory pathways in T1 diabetes and islet cell transplant. She then completed Endocrine fellowship training at Brigham and Women’s hospital, Boston before moving to University of Washington Medical center. She has also received masters in Medical sciences from Harvard Medical School, Boston.

Clinical Interest

Diabetes, Women’s health, Adrenal, Osteoporosis and general Endocrine disorders.

Research Interest

Dr. Subbu Trikudanathan research interest focuses on understanding cardio metabolic risk factors in high risk population. She is currently involved in clinical research trials on diabetes and cardiovascular outcomes.


Comparison of insulin sensitivity measures in South Asians. Trikudanathan S, Raji A, Chamarthi B, Seely EW, Simonson DC. Metabolism. 2013 Jul 29. [Epub ahead of print]

Association of female reproductive factors with body composition:  the   Framingham Heart Study Subbulaxmi Trikudanathan, Alison Pedley, Joseph M. Massaro, Udo Hoffmann, Ellen W. Seely, Joanne M. Murabito and Caroline S. Fox. J Clin Endocrinol Metab. 2013 Jan; 98(1):236-44. Epub 2012 Oct 23.

Immune modulation by lacto-N-fucopentasoeIII in experimental autoimmune encephalomyelitis Zhu B, Trikudanathan S, Zozulya AL, Sandoval-Garcia C, Kennedy JK, Atochina O, Norberg T, Castagner B, Seeberger P, Fabry Z, Harn D, Khoury SJ, Guleria I. Clin Immunol. 2012 Mar; 142(3):351-61. Epub 2011 Dec 30.

Anti- CD3mAb treatment cures PDL1-/- NOD mice of diabetes but precipitates fatal myocarditis. Mfarrej B, Keir M, Dada S, Trikudanathan S, Sayegh MH, Sharpe AH, Guleria I. Clin Immunol. 2012 Mar; 142(3):351-61. Epub 2011 Dec 30.

Comparison of bone mineral density and body proportions between women with complete androgen insensitivity syndrome and women with gonadal dysgenesis. Han TS, Goswani D, Trikudanathan S, Creighton SM, Conway GS. Eur J Endocrinol 2008 Aug; 159(2): 179-85.

Optimal management of steroid treated patients. Trikudanathan S, McMahon GT. Nat Clin Pract Endocrinol Metab. 2008 May; 4(5): 262-71.

Cardio-protective strategies for Type 2 Diabetes. Trikudanathan S, McMahon GT. Journal of clinical outcome management 2008 March; 15(3): 133-147.

The Evolution of the Immunobiology of Costimulatory Pathways: Clinical Implications. Trikudanathan S, Sayegh MH. Clinc Exp Rheumatol 2007 Sep – Oct; 25 (5 Suppl 46): S12-21.

The role of ICOS in auto and alloimmune destruction of islets in NOD mice. Ansari MJ, Fiorina F, Dada S, Guleria I, Yuan X, Trikudanathan S, Smith RN, Freeman G, Sayegh MH. Clin Immunol. 2008 Feb; 126(2):140-7. Epub 2007 Sep 24.

Mechanisms of PDL1-mediated regulation of autoimmune diabetes. Guleria I, Gubbels M, Dada S, Fife B, Ansari MJ, Trikudanathan S, Vadivel N, Fiorina P,Yagita H, Atkinson M, Bluestone JA, Sayegh. Clin Immunol. 2007 Oct;125(1):16-25. Epub 2007 Jul 12.

Transplant tolerance through costimulation blockade –are we there yet? Vadivel N, Trikudanathan S, Chandraker A. Frontiers in Biosciences. 2007 May 1; 12:2935-46

Tuberculous peritonitis: a race against time. Vadivel N, Trikudanathan S, Singh AK. Kidney Int. 2006 Sep; 70(5):969-72. Epub 2006 Jul 5.

Section (b) –Book Chapters

Normal Physiology and disorders of the adrenal cortex and medulla – 2012. Trikudanathan S, Dluhy RG. Chapter contribution to The Brigham Intensive Review of Internal Medicine – Editors Ajay K. Singh, Joseph Loscalzo

Altered adrenal function and Autonomic nervous system -2011. Trikudanathan S, Williams GH. Chapter contribution to Primer in Autonomic nervous system  - Editors David W. Robertson, Philip A. Low, Ronald J. Polinsky

The Adrenocortical dysfunction -2009. Trikudanathan S, Dluhy RG. Chapter contribution to Adrenal Imaging –Editors Blake M, Boland R