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Tracy Tylee, M.D.

Metabolism, Endocrinology and Nutrition

Clinical Assistant Professor of Medicine


Dr. Tylee specializes in endocrinology, with a particular interest in the management of type 1 and type 2 diabetes, adrenal disorders, disorders of calcium metabolism and thyroid disease, including thyroid biopsies.


Dr. Tylee received her medical degree from the University of Washington. She completed her residency training in internal medicine at the University of California San Diego before returning to Seattle for her endocrine fellowship at the University of Washington. Following the completion of her fellowship, she accepted a position at the Diabetes Care Center at the University of Washington. She also spends time in general endocrine clinics at both Harborview and the University of Washington where she is involved in teaching fellows and residents through the training programs at the University of Washington.

Clinical Interest

Dr. Tylee specializes in the care of patients with type 1 and type 2 diabetes. In addition, she is experienced in the management of general endocrine conditions such as thyroid, adrenal and calcium disorders.

Research Interest

Dr. Tylee’s research interests involve ensuring that patients are getting the best quality care for their diabetes, as well as finding ways to improve the delivery of health care.


Tylee T, Trence D. Glycemic variability: looking beyond the A1C. Diabetes Spectrum. 2012;25(3):149-153.

Kaiyala K, Morton G, Thaler J, Meek T, Tylee T, Ogimoto K, Wisse B. Acutely decreased thermoregulatory energy expenditure or decreased activity energy expenditure both acutely reduce food intake in mice. PLoS ONE 2012;7(8):e41473.

Adams K, Holmberg L, Leisenring W, Fefer A, Guthrie K, Tylee T, McDonald G, Bensinger W, Nelson JL.  Risk factors for syngeneic graft-versus-host disease after adult hematopoietic cell transplantation.Blood. 2004;104(6):1894-7.

Adams K, Lambert N, Heimfeld S, Tylee T, Pang J, Erickson T, Nelson JL.  Male DNA in female donor apheresis and CD34-enriched products.  Blood. 2003;102(10):3845-7.

Lambert N, Lo YMD, Erickson T, Tylee T, Guthrie K, Furst D, Nelson JL.  Male microchimerism in healthy women and women with scleroderma: cells or circulating DNA? A quantitative answer.  Blood 2002;100(8):2845-51.

Lambert N, Stevens A, Tylee T, Erickson T, Furst D, Nelson JL.  From the simple detection of microchimerism in patients with autoimmune diseases to its implication in pathogenesis.  Ann NY Acad Sci. 2001;945:164-171.

Lambert N, Distler O, Muller-Ladner U, Tylee T, Furst D, Nelson JL.  HLA-DQA1*0501 is associated with diffuse systemic sclerosis in Caucasian men.  Arthritis and Rheumatism.  2000;43(9): 2005-2101.

Stevens A, Tsao B, Hahn B, Guthrie K, Gazinski A, Lambert N, Porter A, Tylee T, Nelson JL.  Maternal HLA Class II Compatibility in Males with Systemic Lupus Erythematosus.  Arthritis Rheum. 2005;52(9):2768-73.

Tylee T, Trence D. Diabetes and Cancer. EmPower Magazine. 2012;4(4).

Tylee T. Confirming the Diagnosis of Primary Aldosteronism. Endo Trends: A Newsletter of the Endocrine Fellows Foundation. 2011;18(3).


Tylee T, Schwartz M, Kaiyala K, Wisse B. Leptin is Required for the Effect of High Fat Diet to Increase Wheel Running in Mice. Diabetes. 2012;61(suppl 1): 1917-P.

Tylee T, Trence D. Bilateral Adrenal Enlargement Due to Vasculitis. Endocr Rev. 2011;32: P3-547.

Tylee T, Wisse B. Initiation of a High-Fat Diet Increases Voluntary Exercise in Mice. Endocr Rev. 2011;32: P3-364.

Tylee T, Cumming DE.  The role of ghrelin and insulin in cellular signaling in the hypothalamus. J Invest Med 2006;54(1)

Tylee T, Cummings DE.  Effects of ghrelin and insulin on phosphoinositide 3-kinase signaling in the hypothalamus.  Diabetes. 2005;54(S1):A445

Tylee T, Overduin J, Frayo RS, Cummings DE.  Lactulose suppresses ghrelin in a dose-dependent manner.  J Invest Med 2004;52(1):S131

Tylee T, Yee C. Generation of T-T cell hybridomas as a tool for measuring antigen presentation.  J Invest Med  2003;51(1)

Tylee T, Holmberg L, Lambert N, Nelson JL.  Effect of parity on graft-versus-host disease: is fetal microchimerism involved?  FASEB 2002;16(4): A1706