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Wei Hao, M.D., Ph.D.

Metabolism, Endocrinology and Nutrition

Clinical Associate Professor of Medicine
Director, Inpatient Hyperglycemia Consult Service at UWMC


Focus

Development and oversight of a hospital-wide inpatient hyperglycemia consult service at UWMC, leading a team of ARNP, fellows and residents, and ensuing safe transitions between the inpatient and outpatient setting for patients with diabetes and hyperglycemia; development of systems to improve glycemic management within UWMC with a goal to meet hospital quality measures.
In Endocrine care, I have special interest in management of multiple endocrine neoplasia syndromes and parathyroid disorders. I have a long-standing research interest in the pathogenesis, prevention and intervention of type 1 diabetes.



Publications


Hao W, Maclaren NK: Prediction and prevention of insulin-dependent diabetes. Perspectives in General Surgery 2:113-130, 1991.

Mehta V, Hao W, Brooks-Worrell BM, Palmer JP: The functional state of the beta cell modulates IL 1 and TNF induced cytotoxicity. Lymphokine and Cytokine Research 12:255-259, 1993.

Hao W, Serreze DV, McCulloch DK, Neifing JL, Palmer JP: Insulin (auto)antibodies from human IDDM cross-react with retroviral antigen p73. J of Autoimmunity 6:787-798, 1993.

Mehta VK, Hao W, Brooks-Worrell BM, Palmer JP: Low dose interleukin-1 and tumor necrosis factor individually stimulate insulin release but in combination cause suppression. Eur J Endocrinol 130:208-214, 1994.

Hao W, Linsong Li, Mehta V, Lernmark A, Palmer JP: The functional state of the beta cell affects expression of both forms of glutamic acid decarboxylase. Pancreas 9:558-562, 1994.

Hao W, Palmer JP: Recombinant human transforming growth factor ß does not inhibit the effects of interleukin-1ß on pancreatic islet cells. J Interferon & Cytokine Res 15: 1177-1183, 1995.

Hao W, Palmer JP: The effects of cytokines on expression of glutamic acid decarboxylase-65 in cultured islets. Autoimmunity 22:209-218, 1995.

Hao W, Gladstone P, Engardt S, Greenbaum C, Palmer JP: Major histocompatibility complex (MHC) class I molecule expression is normal on peripheral blood lymphocytes from patients with IDDM. J Clin Invest 98:1613-1618,1996.

Hao W, Palmer JP: Islet cell function in type 1 and type 2 diabetes. J Clinical Ligand Assay 21:309-317, 1998

Hao W, Myhre AP, Palmer JP: Nitric oxide mediates IL-1ß stimulation of heat shock protein but not IL-1ß inhibition of glutamic acid decarboxylase. Autoimmunity 29:93-101,1999

Hao W, Davis C, Hirsch IB, Eng LJ, Daniels T, Walsh D, Lernmark A: Plasmapheresis and immunosuppression in Stiff-man syndrome with type 1 diabetes: A two year study. J Neurology 246:731-735,1999

Hao W, Daniels T, Pipeleers , Smismans A, Reijonen H, Nepom GT, Lernmark A: Radioimmunoassay for glutamic acid decarboxylase-65. Diabetes Technology and Therapeutics 1:13-20,1999

Hao W, Davis C, Daniels T, Hampe C, Lernmark A: Epitope-specific glutamic acid decarboxylase-65 autoantibodies in intravenous immunoglobulin preparations. Transfus Med 9(4):307-10, 1999

Hao W, Skarulis MC, Simonds WF, Weinstein LS, Agarwal SK, Mateo C, James-Newton L, Gibril F, Jensen RT, Marx JS: MEN1 Variant with Frequent Prolactinoma and Rare Gastrinoma. J Clin Endocrinol Metab 89(8):3776-89, 2004