

EDUCATION AND TRAINING
Ph.D., Case Western Reserve University, Biochemistry, Cleveland, OH
M.D., Case Western Reserve University, Cleveland, OH
Residency, Boston City Hospital, Boston, MA
Fellowship, University of Washington, Division of Metabolism, Endocrinology and Nutrition,
Seattle, WA
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Edward W. Lipkin, M.D., Ph.D.
Associate Professor of Medicine
Division of Metabolism, Endocrinology and Nutrition
OFFICE ADDRESS
University of Washington Medical Center
1959 NE Pacific Street
UW Mailbox 356426
Seattle, WA 98195-6426
CURRENT RESEARCH INTERESTS
Clinical trials: 1) Action to Control Cardiovascular Risk
in Diabetes (ACCORD); 2) Outcomes of Weight Loss in Type 2 Diabetes
(LOOK Ahead). Investigation of disorders of bone and mineral metabolism including:
1) osteoporosis, 2) bone and mineral metabolism in pregnancy and
lactation; 3) abnormalities
of bone physiology in short-gut patients; and, 4) impact of parenteral nutrition on bone histology and bone mineral
metabolism.
REPRESENTATIVE PUBLICATIONS
Lipkin EW, Teller DC and de Haën C: Kinetics of insulin binding to rat white fat cells
at 15°C. J Biol Chem 261:1702-1711, 1986.
Lipkin EW, Ott SM and Klein GL: Heterogeneity of bone histology in parenteral nutrition
patients. Am J Clin Nutr 46:673-680, 1987.
Lipkin EW: A longitudinal study of calcium regulation in a nonhuman primate model of
parenteral nutrition. Am J Clin Nutr 67:246-254, 1998.
Ott SM, Lipkin EW and Newell-Morris LL: Physiological
adaptations of bone associated with pregnancy and lactation in young
macaques. J Bone Min Res 14:1779-1788, 1999.
Lipkin EW, Aumann CA and Newell-Morris L: Evidence for common
controls over inheritance of bone quantity and body size from
segregation analysis in a pedigreed colony of nonhuman primates (macaca
nemistrina). Bone 29:249-257, 2001. Diabetes Prevention
Research Group: Reduction in the incidence of type 2 diabetes
with lifestyle intervention and metformin. N Engl J Med
346:393-403, 2002.
Diabetes Prevention Research Group: Effects of withdrawal from
metformin on the development of diabetes in the diabetes prevention
program. Diabetes Care 26:1306-1308, 2003.
Reboussin DM, Goff DC Jr, Lipkin EW, Herrington DM, Summerson J,
Steffes M, Crouse RJ 3rd, Jovanovic L, Feinglos MN, Probstfield JL,
Banerji MA, Pettit DJ and Williamson J: The combination oral and
nutritional treatment of late-onset diabetes mellitus (CONTROL DM)
trial results. Diabet Med 21:1082-1089, 2004.
Ginsberg HN, Bonds DE, Lovato LC, Crouse JR, Elam MB, Linz PE,
O'Conner PJ, Leiter LA, Weiss D, Lipkin E, Fleg JL, and the ACCORD
Study Group: Evolution of the lipid trial protocol of the Action
to Control Cardiovascular Risk in Diabetes (ACCORD) Trial. Am J
Cardiol 99:56i-67i, 2007.
The ACCORD Study Group: Action to Control Cardiovascular Risk in
Diabetes (ACCORD) Trial: Design and Methods. Am J Cardiol
99:21i-33i, 2007.
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