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Announcements:

Congratulations to Houra Merrikh, Assistant Professor, UW Microbiology, and recipient of the presitgious NIH Director's New Innovator Award. She is one of three recipients at the UW to receive this award as part of the NIH High Risk-High Reward Program.

Congratulations to E. Peter Greenberg, Professor, UW Microbiology, and recipient of the Doctor of Science Honoris Causa, June 13, 2013, from the University of Guelph, Ontario, Canada.


Upcoming Seminars:

**PLEASE NOTE THE LOCATION**
June 17, 2014, 4:00 PM, T-747 Health Sciences Building

Angela L. Rasmussen, Ph.D.
Research Scientist
Department of Microbiology
University of Washington

"The New Supermodels: Studying Emerging Virus Pathogenesis in Novel Model Systems"

Pathogenesis models are essential to investigating host responses to virus infection that are linked to disease, as well as for the development of therapeutics and vaccines. For emerging viruses, a pathogenesis model is essential for the rapid development and deployment of countermeasures needed to contain epidemic spread during an outbreak. However, often in the case of a newly emerging virus, identifying a model that accurately recapitulates key features of viral disease can be challenging and time-consuming, particularly for highly pathogenic viruses requiring secure biocontainment. My research employs multiple systems approaches to identify and rapidly characterize novel rodent and non-human primate models for emerging viruses, including Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and Ebola hemorrhagic fever. Importantly, these new models reproduce disease observed in human patients, allowing us to study pathogenic mechanisms caused by virus replication, host-pathogen interactions, host responses to infection, and host genetics predisposing clinical outcome. These models can now be used to identify novel drug targets, repurpose existing drugs that may ameliorate disease, and evaluate candidate therapeutics and vaccines.


 

 

 
 
   
 
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Department of Microbiology · University of Washington · Box 357735 · Seattle WA 98195-7735 · phone: (206) 543-5824 · fax: (206) 543-8297 · micro@u.washington.edu