Cell Biology of Bacterial Infection
Listeria monocytogenes (green) interacting with macrophages (red/blue).
Credit: Michelle Reniere
UW Microbiology Home
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Interspecies Interactions
The tiny obligate parasitic bacterium Southlakia epibionticum(yellow) cultured on its host bacterium, Actinomyces israelii (blue)
Image credit: Drs. Larry Gallagher and Joseph Mougous
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Bacterial Self-Organization
Pseudomonas aeruginosa cells that engage (magenta) or don’t (green) in collective behavior spontaneously self organize in cellular aggregates (3D image acquired by confocal laser scanning microscopy).
Credit: Jeffrey Carey and Matt Parsek
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Phage antagonize CRISPR-Cas Immunity
Cryo-EM structure of a phage-encoded anti-CRISPR protein (blue) in complex with the RNA-targeting CRISPR effector Cas13 (gray) and its guide RNA (red).
Credit: Alex Meeske
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Emergence of Highly Pathogenic Clones of Escherichia coli
Genetic typing of uropathogeic E. coli reveals strong association of some clones with high sensitivity or extreme resistance to multiple antibiotics.
Courtesy: Sokurenko Lab
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Quorum sensing in Vibrio fischeri
Lux genes coding for light production are activated by quorum sensing at high cell density. The light produced by the bacteria exposed the film for the image.
Courtesy: Greenberg Lab
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Pseudomonas aeruginosa in co-culture
Structural component of bacterial targeting type VI secretion system P. aeruginosa (green) assembled in presence of competitor organism (red).
Courtesy of: Mougous Lab
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HIV-1 Envelope Evolution
Reconstructed phylogenetic network of HIV-1 envelope sequences (C2-V5) from subtype B.
Courtesy of: Mullins Lab
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Pseudomonas aeruginosa
Colonies of Pseudomonas aeruginosa expressing different amounts of exopolysaccharides.
Courtesy of: Harwood Lab
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YopM Crystal Structure
Crystal structure of the Yersinia virulence protein YopM
Courtesy of: Cookson Lab
News & Updates
Sora Kim (Guo Lab) won 3 years of postdoctoral research support as part of this prestigious fellowship. Congrats Sora!
Micro PhD student Ella Lamont (Sherman Lab) was accepted into the TL1 Translational Research Training Program, a one-year mentored research training program in translational science for predoctoral students. Congratulations!
Congratulations to Edith Sawyer (Meeske Lab) and Billy Ngo (Mougous Lab), who received support from the NSF Graduate Research Fellowship Program!
As part of the Science in Medicine series, Professor Greenberg will be giving his lecture, “Shedding light on bacterial communication and cooperation”, on April 17th at 11AM in the Orin Smith Auditorium, and over Zoom. RSVPs here are appreciated but not required.
Upcoming Events
Seminar
**Genome S060 Foege Auditorium**
Speaker:
Dr. Bryan Dewsbury
Recent Publications
Science translational medicine
Apr, 2024
bioRxiv : the preprint server for biology
Mar, 2024
bioRxiv : the preprint server for biology
Mar, 2024
Fast Facts
