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Charles A. Evans, Ph.D. (1912-2008)
 
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Announcements:

We are conducting a search for an Assistant Professor in bacteriology. An ideal candidate will bring an innovative research program that synergizes with existing strengths of the department in the areas of bacterial pathogenesis, bacterial cell biology and/or microbial communities; however, all highly qualified individuals pursuing cutting-edge bacteriology research are encouraged to apply. Our department is a collegial, vibrant, interactive community of researchers who are committed to world-class science and training at all levels, including supporting the development of junior faculty. Located in Seattle, the department is part of an extensive network of research institutes and institutes of higher learning that offer a wealth of resources and opportunity for collaboration. All University of Washington faculty engage in teaching, research and service. The position is a full-time, tenure track position in the School of Medicine. Applicants should have a Ph.D., M.D., or foreign equivalent. For consideration, please submit a cover letter, curriculum vitae, research prospectus, reprints or preprints as a single PDF, a brief statement regarding your teaching experience and/or philosophy, and 3 confidential references via Interfolio (http://apply.interfolio.com/25379). Please note the Interfolio reference process requires you to request references through Interfolio and then return to Interfolio to apply those references to your application after your referee submits them. Applications received by October 24th, 2014 will be given priority review. University of Washington is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sex, age, status as protected veterans, or status as qualified individuals with disabilities.

For questions about this position, please email bbh@uw.edu.


Upcoming Seminars:

November 18, 2014, 4:00 PM, HSB T-639

Jörn Coers, Ph.D.
Assistant Professor
Department of Molecular Genetics and Microbiology
Duke University Medical Center

"IFN-inducible GTPases in host resistance and inflammation"

The main focus of my laboratory is to study mechanisms by which mammalian host cells capture and eliminate cell-invading bacterial pathogens. Critical for the successful entrapment and destruction of intracellular pathogens are families of Interferon-inducible GTPases, known as Guanylaye Binding Proteins (GBPs) and Immunity Related GTPases (IRGs). Members of these two GTPase families can specifically bind to pathogen-containing vacuoles (PVs), but the mechanism of immune recognition is poorly defined. Current research in my lab aims to find answers to 3 main questions: 1) how do GBP and IRG proteins recognize PVs as non-self structures? 2) What are the pathways of cell-autonomous resistance controlled by GBPs and IRGs? 3) How do GBP- and IRG-mediated innate immune responses shape the adaptive immune responses to bacterial pathogens such as Chlamydia trachomatis?


 

 

November 25, 2014, 4:00 PM, HSB T-639

Jia Zhu, Ph.D.
Research Assistant Professor
Department of Laboratory Medicine
University of Washington

"Local Power: Tissue Resident Immunity in Human HSV-2 Infection"

Recently, tissue resident T-cell memory has been implicated to provide a first line of defense superior to its circulating counterpart against recurrent infection at the body’s barrier surface. Understand the mechanisms of this immediate and localized protection is critical for designing effective vaccines against sexual transmitted pathogens, such as HSV and HIV. We have used the recurrent genital herpes disease as a human model system to investigate the spatial dynamics, local persistence, antiviral function and repertoire diversity of tissue resident memory T cells in genital skin and mucosa. Here, I will describe the in situ functional characterization of local and immune components in the context of tissue microenvironment, and discuss the potential roles of tissue resident memory T cells in promoting intrinsic immunity in an organ-wide protection against re-infection.


 

 

 
 
   
 
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Department of Microbiology · University of Washington · Box 357735 · Seattle WA 98195-7735 · phone: (206) 543-5824 · fax: (206) 543-8297 · micro@u.washington.edu