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Marsha R. Penner, PhD

Professional Infomation

Marsha Penner


Penner, M.R., Roth, T.L., Chawla, M.K., Hoang, L.T., Roth, E.D., Lubin, F.D., Sweatt, D.J., Worley, P.F. & Barnes, C.A. Age-related changes in Arc transcription and DNA methylation within the hippocampus. (2010). Neurobiology of Aging, in press.

Penner MR, Roth TL, Barnes CA, Sweatt JD. (2010). An epigenetic hypothesis of aging-related cognitive dysfunction. Frontiers in Aging Neuroscience. 12;2:9.
McGlone, J., Valdivia, I., Penner, M., Williams, J., Sadler, R.M., Clarke, D.B. (2008). Quality of life and memory after vagus nerve stimulator implantation for epilepsy. Canadian Journal of Neurological Sciences., 35:287-96.

Burkes, S.N., Chawla, M.K., Penner, M.R., Crowell, B.E., Worley, P.F., McNaughton, B.L. & Barnes, C.A. (2005). Differential encoding of behavior and spatial context in deep and superficial layers of the neocortex. Neuron, 45, 667674.

Pinaud, R., Tremere, L.A., Penner, M.R., Hess, F., Robertson, H.A. & Currie, R.W. (2002). Plasticity-Driven Gene Expression in the Rat Retina. Molecular Brain Research, 98, 93-101.

Pinaud, R., Tremere, L.A., Penner, M.R., Robertson, H.A. & Currie, R.W. (2002). Complexity of sensory environment drives the expression of candidate-plasticity gene, nerve growth factor induced-a.  Neuroscience, 112, 573-582.

Penner, M.R., McFadyen, M.P., Pinaud, R., Carrey, N., Robertson, H.A. & Brown, R.E. (2002). Age-Related Distribution of C-fos Expression in the Striatum of CD-1 Mice After Acute Ritalin Administration. Developmental Brain Research, 135, 71-77.

Penner, M.R., McFadyen, M.P., Carrey, N. & Brown, R.E. (2001). Methylphenidate Hydrochloride Does Not Affect Ultrasonic Vocalizations or Neuromotor Development of 3-11 Day Old Mouse Pups. Developmental Psychobiology, 39, 216-228.


Research Interests:

In general I am interested in how the brain processes information necessary for optimal decision making, and how this affects learning and memory function. In addition, I am interested in how these processes change during the course of normal aging.


2008    Doctor of Philosophy, Neuroscience, University of Arizona, Tucson, Arizona
Dissertation: “Subregion Specific Changes in Immediate-Early Genes in the Aged Hippocampus”

2001    Master of Science, Pharmacology & Neuroscience, Dalhousie University, Halifax, Nova Scotia
Dissertation: “The Role of Immediate-Early Genes in the Development of Kindling”

1998    Bachelor of Arts Honors, Psychology, University of Winnipeg, Winnipeg, Manitoba
Honors Thesis: “The Effects of Estrogen on Brain Lateralization and Spatial Ability”