Welcome to Lidstrom Laboratory

The Lidstrom laboratory is located in the Departments of Microbiology and Chemical Engineering at the University of Washington in Seattle, WA.

Research in Dr. Lidstrom's laboratory is focused on molecular and metabolic manipulations of methylotrophic bacteria, which are capable of growth on methane, methanol, and methylated amines. The long-term goal of this research is to develop environmentally sound and economically viable alternatives to current chemical production and cleanup strategies. Genetic, physiological and metabolic modeling approaches are used to understand key metabolic pathways in these bacteria, with the goal of directed manipulation of key metabolic pathways and enzymes. The laboratory's recent discovery that methylotrophic bacteria contain a metabolic pathway previously thought to be found only in methanogenic archaea has generated a new research thrust focused on evolution of C1 metabolic pathways across the bacterial/archaeal boundaries. These studies are now being augmented by genomic approaches, including proteomics and expression microarrays.

Phone: (206)-616-5282
Fax: (206) 616-5721
lidstrom@u.washington.edu