G. A. Nagana Gowda, PhD

  • Researcher, Mitochondria and Metabolism Center

  • Research Assistant Professor of Anesthesiology & Pain Medicine

  • Researcher, Northwest Metabolomics Research Center

Research Interests

My research interests are in the area of metabolomics, both methods development and applications focusing investigations of human health and diseases. Our methods development, utilizing nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) techniques, is focused on the analysis of metabolites in complex biological mixtures from humans, animal models and cell lines. We also combine NMR and MS techniques to exploit their combined strength to unravel the biological complexity and identify and quantify unknown metabolites. We are particularly interested in enhancing the NMR’s detection sensitivity and resolution with a view to expand the pool of quantifiable metabolites for metabolomics applications. As a part of this aim, we develop and utilize smart isotope tags that possess dual characteristics – stable isotope for NMR’s sensitivity and permanent charge for MS’s sensitivity- and enable exploiting the combined strength of two bioanalytical platforms.

Education

BS Mysore University, Chitradurga, India. 1983
MS Mysore University, Mysore, India, 1985
PhD Bangalore University, Bangalore, India, 1999
Postdoctoral Scientist   State University of New York, Buffalo, NY, USA, 1998

Honors and Awards

1994  Bruker Young Scientist Award
2003  Elected Fellow, The National Academy of Sciences, India 
2004  NMR Society Award: National Magnetic Resonance Society, India
2006   Elected Member, The National Academy of Sciences, India

Selected Publications

 Laboratory:  Raftery Lab

Contact Information

Mitochondria and Metabolism Center
850 Republican Street, Room C429
University of Washington, Box 358057
Seattle, WA 98109-8057
Phone: 206-543-5336
Fax: 206-616-4819
Email: Nagana Ajjappa