- NMR Facility
- About Us
Anush Oganesian, PhD
- Researcher, Mitochondria and Metabolism Center
- Assistant Professor, Anesthesiology and Pain Medicine
- Molecular mechanisms triggered by stress hormone receptors (α1aAR) in health and disease
- Functional studies of human α1aAR genetic variants in cardiovascular disorders
- G-protein-coupled receptor (GPCR) signaling and extracellular matrix proteins
- Gene editing, cell reprogramming and stem cell models of human cardiovascular diseases
- 1993 George Soros Foundation Prize for Outstanding Results in Basic Sciences
- 1999-2001National Research Scholarship Award (NRSA), NIH
- 2010 National Science Foundation Merit Grant
- American Heart Association
- American Societyfor Pharmacology and Experimental Therapeutics
- American Society for Biochemistry and Molecular Biology
- American Society of Matrix Biology
- National Institutes of Health, R37 HL049103, (Sub-contract) "Subcellular distribution and regulation of alpha1a-adrenoceptors"
- Oganesian A, Yarov-Yarovoy V, Parks W, Schwinn DA. Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway.2011, Proc Natl Acad Sci 108:19796-19801.
- Schwinn DA, Kleine-Bruggeney M, & Oganesian A. Why Do “Similar” Patients Have Different Outcomes. 2011, https://client.blueskybroadcast.com/IARS/2011/abstracts/11_RCL_Schwinn.pdf
- Caromile LA, Oganesian A, Coats SA, Seifert RA, Bowen-Pope DF. The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.2010,
- J Biol Chem285:10487-10496.
- Oganesian A, Armstrong LC, Migliorini MM, StricklandDK, Bornstein P. Thrombospondins use the VLDL receptor and a non-apoptotic pathway to inhibit cell division in microvascular endothelial cells. 2008, Mol Biol Cell 18:563-71.
- OganesianA, Au S, Horst JA, Holzhausen LC, Macy AJ, PaceJM, BornsteinP. The NH2-terminal propeptide of type I procollagen acts intracellularly to modulate cell function. 2006, J Biol Chem 281:38507-18.
- Oganesian A, Poot M, Daum G, Coats SA, Wright MB, Seifert RA, Bowen-Pope DF. Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation. 2003, Proc Natl Acad Sci U S A 100:7563-68.
Mitochondria and Metabolism Center
850 Republican St, Room N121
Seattle, WA 98109-8057