Rong Tian, MD, PhD

  • Director, Mitochondria and Metabolism Center
  • Co-director, NMR center
  • Professor, Anesthesiology and Pain Medicine, Bioengineering
  • Adjunct Professor, Biochemistry, Pathology

Research Interest

  • Energy metabolism in cardiovascular diseases
  • Mitochondrial dysfunction and metabolic signaling
  • NMR spectroscopy and Imaging-guided spectroscopy

Honors and Awards

  • 2004        Young Investigator Award of the American Physiological Society
  • 2003-07   Established Investigator of the American Heart Association
  • 2008        Elected to American Society of Clinical Investigation
  • 2010        Distinguished Achievement Award, American Heart Association Basic Science Council

Selected Publications

  • Karamanlidis G, Lee CF, Garcia-Menendez L, Kolwicz Jr. SC, Suthammarak W, Gong G, Sedensky MM, Morgan PG, Wang W, Tian R. Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure. Cell Metabolism. 2013 Aug 6;18(2):239-250.
  • Kolwicz Jr. SC, Olson DP, Marney LC, Garcia-Menendez L, Synovec RE, Tian R. Cardiac-specific deletion of acetyl CoA carboxylase 2 (ACC2) prevents metabolic remodeling during pressure-overload hypertrophy. Circ Res 2012, Aug 31; 111(6): 728-38. PMID: 22730442
  • Karamanlidis G, Nascimben L, Couper GS, Shekar PS, Tian R. Defective DNA replication impairs mitochondrial biogenesis In human failing hearts. Circ Res. 2010.
  • Yan J, Young ME, Cui L, Lopaschuk GD, Liao R, Tian R. Increased glucose uptake and oxidation in mouse hearts prevents high fatty acid oxidation but causes cardiac dysfunction in diet-induced obesity. Circulation 2009; 119:2818-2828.
  • Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M , Seidman CE, Seidman JG, Ingwall JS ,Balschi JA, and Tian R. Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest. 2007; 117(5):1432-9.

Laboratory

Contact Information

Mitochondria and Metabolism Center
850 Republican Street, Room N130
University of Washington, Box 358057
Seattle, WA 98109-8057
Phone: 206-543-8982
Fax: 206-616-4819
Email: Rong Tian