University of Washington

Course Materials - Conj 504

  Course Chairs: Ray Monnat (UW) & Patrick Duffy (SBRI)
   

Session 1

May 2, 2007

Prof. Brian Greenwood

"The Global Burden of Malaria - Where do we start? What do we do?"

(PowerPoint slides - Part I)
(PowerPoint slides - Part II)

 

The global distribution of clinical episodes of Plasmodium
falciparum malaria
(supp. info)

 

The economic and social burden of malaria

 

Malaria

   

Session 2

May 9, 2007

Prof. Janet Hemingway

"Malaria: Vector borne disease dynamics and vector control"

 

(PowerPoint slides)

 

The Anopheles gambiae detoxification chip: A highly specific
microarray to study metabolic-based insecticide resistance
in malaria vectors

 

The Innovative Vector Control Consortium: improved control
of mosquito-borne diseases

 

Health risks and benefits of bis(4-chlorophenyl)-1,1,1-trichloroethane (DDT)

  The Ecology of Genetically Modified Mosquitoes
  Malaria Control with Genetically Manipulated Insect Vectors
   

Session 3

May 16, 2007

Dr. Thomas E. Wellems

"Treating malaria: What works, what doesn't and what's new"

 

(PowerPoint slides)

 

Malaria Websites

 

Antimalarial Drug Therapy: The Role of Parasite Biology and Drug Resistance

 

Chloroquine-Resistant Malaria

  Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial
   

Session 4

May 23, 2007

Dr. Patrick Duffy

"Pathogenesis of malaria: Who gets sick, who dies and why?"

 

Adherence of Plasmodium falciparum to Chondroitin Sulfate A in the Human Placenta

 

The pathogenic basis of malaria

 

Hypertension and Maternal-Fetal Conflict during Placental Malaria

 

Negative epistasis between the malaria-protective effects of α+-thalassemia and the sickle cell trait

   

Session 5

May 30, 2007

 

Dr. Stefan Kappe

"Malaria vaccines: New strategies for malaria prevention"

 

Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity

 

Genetically modified Plasmodium parasites as a protective experimental malaria vaccine

 

High road, low road? Choices and challenges on the pathway to a malaria vaccine

  Immune responses to Plasmodium vivax pre-erythrocytic stage antigens in naturally exposed Duffy-negative humans: a potential model for identification of liver-stage antigens
   

Any use of lecture materials posted requires permission of author and credit to author.

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