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Faculty Members
A | B | C | D | F | G | H | J | K | L | M | N | O | P | R | S | T | V | W | Y | Z
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Chen Anatao
Electrical Engineering
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Research Interests
Our photonics research includes nonlinear optical polymer materials and optical waveguide devices, fiber optic devices for telecommunication and radio frequency applications, optical sensors for bio and chemical detections, nan-photonics and scattering and spectroscopy of terahertz radiation generated by ultra-fast (fs) laser. We work closely with world's leading chemists and material scientists at the University of Washington on multidisciplinary research to pursue a diverse range of topics on synthesized, self-assembled, and nano scale materials with unique linear and nonlinear optical properties, and we use these new materials to demonstrate new applications and state-of-art devices. The group also has active and productive collaborations with industrial companies and academic institutions.
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Charles Asbury
Physiology and Biophysics
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Research Interests
Our lab studies the mitotic spindle, a molecular machine that organizes and separates duplicated chromosomes during cell division, thereby ensuring equal partitioning of the genetic material. To uncover how this machine operates, we are reconstituting spindle functions using pure components and applying new biophysical tools for manipulating and tracking individual molecules, such as laser trapping and ultrasensitive fluorescence microscopy.
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William M. Atkins
Medicinal Chemistry
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Research Interests
Our lab studies enzymes and proteins that participate in the detoxification of foreign chemicals, including therapeutic drugs. We are also studying therapeutic antibodies, other pharmaceutically important proteins, and several classes of nanoparticles to understand structure-function aspects of their tissue targeting, clearance, and in vitro stability.
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Karl F Böhringer
Electrical Engineering
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Research Interests
In our lab, we work on many aspects of micro and nano electro mechanical systems (MEMS / NEMS). This research tends to be very interdisciplinary, and we have collaborations in biology, chemical engineering, bioengineering, computer science, and other departments. We have built, for example, self-assembling microstructures, biomedical implants, systems for docking of picosatellites, and walking microrobots.
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David Baker
Biochemistry
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Research Interests
Professor Baker's research aims to predict the structures of naturally occurring biomolecules and interactions and to design new molecules with new and useful functions. Building on intial computational designs, Baker uses experiment to better understand the principles underlying catalysis and binding in order to design novel proteins and enzymes.
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François Baneyx
Chemical Engineering
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Research Interests
Our research aims to improve the expression and folding of heterologous proteins in Escherichia coli, develop innovative sensors and sensing strategies, and build proteins capable of controlling the nucleation, growth, crystallography, assembly and reconfiguration of hybrid organic-inorganic-synthetic materials at the nanoscale.
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Rajendra Bordia
Materials Science and Engineering
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Research Interests
Our research is at the intersection of materials science and mechanics and is focused on fundamental and applied studies in the processing and properties of complex material systems for energy, environmental and high temperature applications. Current emphasis is on integrating multi-scale simulations and experimental research to design complex microstructures. Projects are in the areas of constrained processing of multilayered ceramics including solid-oxide fuel cells, control of nanostructure and its effect on properties of complex oxides including ion conducting and thermoelectric oxides, processing and properties of hierarchical porous ceramics including electrochemical systems and membranes, and ceramics from molecular precursors including composites, coatings and porous ceramics.
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Charles Campbell
Chemistry
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Research Interests
Improving catalysts could minimize the use of fossil fuels, thus helping solve the energy crisis while decreasing greenhouse gases. Our group tries to clarify why catalyst modifiers act to promote catalytic activity or selectivity, and how nanoscale features of the catalyst surface can tuned to make better catalysts. In solar cells and LEDs, charge injection and extraction occurs at the interface between a metal or other conductor and one of the semiconducting materials (inorganic materials in most current commercial devices, but hopefully cheaper-to-make polymer films in the future). We also study the energetics and electronic properties of these interfaces.
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Guozhong Cao
Materials Science and Engineering
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Research Interests
Nanorods by sol electrophoretic deposition, mesoporous materials, piezoelectric-based sensors and actuators, photoelectrochemical cells, nanoscale sensors and detectors
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David Castner
Chemical Engineering
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Research Interests
Our research is directed at obtaining detailed information about the surface composition and structure of biomaterials and the interaction of biomolecules with those biomaterials. Recent advances have made it possible to control chemistry on a local scale undreamed of only a few years ago. The dimensions of the lateral chemical variations are diminishing, the complexity of the molecules being introduced at the surface is increasing, and the manipulations of the surface moieties become ever more sophisticated. These advances offer great challenges and opportunities for biomedical surface analysis.
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Daniel Chiu
Chemistry
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Research Interests
Nanofabrication, Microfluidics, Laser Microscopy, Spectroscopy, Single Molecule Detection, Single Cells, Single Organelles
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Howard Chizeck
Physics
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Research Interests
Control engineering theory and the application of control engineering to biomedical problems and biologically-inspired engineered systems. Closed Loop Drug Delivery. Application of systems theory to problems in genomics and proteomics,and to self-assembly.
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Jae-Hyun Chung
Mechanical Engineering
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Research Interests
MEMS/Nanotechnology area, and in particular of the fabrication of micro/nano structures. Examples of the research area are electric field guided nanowire assembly, reactive ion etching assisted nanopore fabrication, and nanoscale gap fabrication.
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Valerie Daggett
Bioengineering
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Research Interests
Single-molecule atomic characterization of structure and dynamics
Drug Design
Biosensor and biomaterial design
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Larry Dalton
Chemistry
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Research Interests
The Dalton research group designs nanometer and sub-nanometer molecules for assembly into lattices of controlled dimensionality including fractional dimensionalities and for controlled molecular cooperativity to achieved desired viscoelasticity. In particular, we focus on molecules with extended pi electron delocalization. Control of the organization of these molecules is critical to the optimization of physical properties including optical, electronic, magnetic, and optoelectronic properties.
We also are developing new measurement techniques for definition of molecular order, lattice dimensionality, and nanoscopic molecular cooperativity and new coarse-grained statistical mechanical simulations for understanding the effects of intermolecular interactions in understanding the structure and dynamics of such nano-engineered materials.
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Santosh Devasia
Mechanical Engineering
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Research Interests
The Devasia group research interest includes the development of high-speed nano-positioning systems, for applications such as nano-imaging, nano-manufacturing, nano-robotics, structural control of precision telescopes, and high-density information storage. For example high-speed nano-positioning is needed to position probes (without causing damage of soft samples) in Atomic force microscopes (AFMs) when imaging soft samples such as polymers and human cells. The goal is to reduce the imaging time from 10-20 minutes to 10-20 seconds (per frame) without causing sample damage/distortion or reducing the area that can be imaged. High-speed precision AFM will enable investigations of important issues in health and disease such as the effects of aging on cell migration
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Scott Dunham
Electrical Engineering
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Research Interests
Professor Dunham's MolES-related interests lie in modeling and simulation of chalcopyrite (CIGS and CZTS), silicon and polymer photovoltaics. Efforts within the Nanotechnology Modeling Laboratory are focused on obtaining basic understanding of nanofabrication processes and device operation and applying that knowledge to produce better models, simulators, and devices.
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Albert Folch
Bioengineering
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Research Interests
The Folch Lab exploits microfluidic technology to better mimic the microenvironment of nerve and cancer cells when we culture them outside of the organism. We are interested in studying how neurons find their target during development (axon guidance), how they establish their connections (synaptogenesis), and how they sense odors (olfactions). We are also using microfluidic approaches to develop inexpensive blood tests for measuring tumor progression, assays to test personalized chemotherapies outside of the human body, and automated platforms for immunotherapy.
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Daniel Gamelin
Chemistry
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Research Interests
Professor Gamelin's research targets the development and physical characterization of new functional inorganic materials, with particular focus on semiconductor nanostructures and thin films for photophysics, spin-photonics, and solar energy conversion.
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Xiaohu Gao
Bioengineering
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Research Interests
Ultrasensitive detection,
Molecular Imaging and Screening,
Imaging instrumentation,
Our group designs and develops functional materials and structures on the nanometer scale. Examples include multicolor quantum dots for fluorescence imaging, magnetic nanoparticles for MRI, metallic nanoparticles for ultrasensitive detection, and polymeric nanoparticles for targeted drug delivery. Most recently, we are developing multimodality imaging probes by combining different materials into discrete nanostructures in order to utilize the strength of each individual component.
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David S. Ginger
Chemistry
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Research Interests
The Ginger Research Group pioneers techniques such as time-resolved electrostatic force microscopy (trEFM) and photoconductive atomic force microscopy (pcAFM) to study nanostructured solar cells, energy efficient light-emitting diodes, and biosensors.
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John A. Glomset
Biochemistry
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Research Interests
Members of the Glomset group are currently investigating the molecular mechanisms that operate in a macaque monkey orbitofrontal cortex that we obtained via the tissue distribution program of the Regional Primate Research Center here.
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Allan Hoffman
Bioengineering
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Research Interests
Has retired and is doing a research project in Korea as a part-time position and a collaboration. He still maintains an office at UW.
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Alex K-Y Jen
Materials Science and Engineering
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Research Interests
Alex Jen's research employs the "molecular engineering" approach to tailor size, shape, sequence, and functionality of organic/hybrid functional materials to explore their extraordinary properties. Utilize molecular, polymeric, and biomacromolecular self-assembly to create ordered arrangement of organic and inorganic functional materials for photonics, opto-electronics, energy, sensing, nanomedicine, and nanotechnology.
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Samson Jenekhe
Chemical Engineering
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Research Interests
Our research is focused on the molecular engineering of organic and polymeric materials for electronic, photonic, and energy applications. Our studies include synthesis, processing, self-assembly, structure-property relationships, photophysics, and charge transport of organic and polymer semiconductors. Ongoing device engineering applications include thin film transistors, photovoltaic cells, light emitting diodes, and photodetectors.
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Shaoyi Jiang
Chemical Engineering
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Research Interests
Dr. Jiang's research is on biointerfaces, biomaterials and biosensors, particularly the molecular understanding, design and development of zwitterionic functional materials. His work spans from molecular principles to product development for a wide range of applications such as medical devices, nanoparticles for diagnostics and drug delivery, antimicrobial coatings and marine coatings.
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Werner Kaminsky
Chemistry
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Research Interests
The research is aiming at the correlation between molecular structure and observed optical properties to study the anisotropic interaction of molecules with light. New closely related chiral substances are synthesized as models for structure-feature studies. New optical measurement techniques are developed to collect data on chiroptical properties like optical rotation, circular dichroism, the electro-optic effect, and electrogyration. Semi-empirical models are developed to be applied to the visible spectral range of light which allow calculating birefringence, electrogyration, the electro-optic effect and the d-coefficients for frequency doubling, using the molecular structure and empirical polarizability volumes for the individual atoms.
Crystal growth from aqueous or other solutions and their crystallographic characterization (morphologies, structure, and basic physical properties) assist the research. The aim is to provide large samples of interesting chemical composition in the size-range of cube-centimeters. X-ray structure determination, the likely first technology to resolve matter on a nano meter scale, complement these studies.
I devoted some of my time to the development of software packages to aid the teaching of physical crystallography. This resulted in programs running on Windows for the presentation of tensorial features in form of representation surfaces, for the presentation of crystal morphology as virtual reality models, and for visualizing structures.
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Sarah Keller
Chemistry
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Research Interests
The Keller Group applies concepts and experimental tools from the fields of physical chemistry and condensed matter physics (e.g. phase transitions, miscibility, critical phenomena, and diffusion) to investigate self-assembling amphiphiles, with particular focus on inhomogeneous distributions of lipids within membranes that model cell membranes.
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Deok-Ho Kim
Bioengineering
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Research Interests
Our research spans the disciplinary boundaries between cell mechanobiology, nanobiotechnology, and biomaterials with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale fabrication and integration tools, we focus on the development and applications of biomimetic cell culture models and functional tissue engineering constructs for high-throughput drug screening, stem cell-based therapies, disease diagnostics, and medical device development. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic and molecular insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health.
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Eric Klavins
Electrical Engineering
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Research Interests
The Klavins Lab uses tools and methodologies from electrical engineering and computer science to develop detailed mechanisms that will inform the development of novel biological systems in the emerging field of synthetic biology. Topics of research interest include gene expression, auxin signal processing, synthetic multi-celled systems, and directed evolution.
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Kannan Krishnan
Materials Science and Engineering
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Research Interests
Materials Science with emphasis on nanoscale magnetic and transport (both charge and spin) phenomena in reduced dimensions, including their inter-coupling, to develop new paradigms for materials and devices in the context of novel information (storage, processing and logic) and energy technologies. And Bioengineering at the intersection of Magnetism, Materials and Medicine focusing on diagnostics, imaging and therapy, with appropriate translational research and commercialization activities.
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Jiangyu Li
Mechanical Engineering
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Research Interests
Our group is devoted to investigating the mechanics and physics of multifunctional materials and systems using tightly combined theoretical, numerical, and experimental investigations. We are interested in understanding the formation and evolution of microstructure in materials, clarifying their structure-property relationship, and optimizing microstructures and processing conditions for superior functional properties. We have been working on ferroelectrics, ferromagnetic materials, multiferroics, thermoelectrics, and electro-active polymers and composites, and we are currently focusing on global energy need through multifunctional materials design and synthesis. We are also probing electromechanical coupling in biological systems using piezoresponse force microscopy, with which we recently discovered biological ferroelectricity in soft tissues.
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Xiaosong Li
Chemistry
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Research Interests
Nano research in the Li group focuses on developing and applying electronic structure theories and ab initio molecular dynamics for studying properties and reactions that take place in large systems, such as polymers, biomolecules, and nanostructures.
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Mary Lidstrom
Chemical Engineering
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Research Interests
Research in Dr. Lidstrom's laboratory is focused on genome-scale analyses and manipulations of the metabolic network in methylotrophic bacteria, which are capable of growth on methane, methanol, and methylated amines. The long-term goal of this research is to develop environmentally sound and economically viable alternatives to current chemical production strategies, including conversion of natural gas to liquid fuels (Gas-To-Liquid technology).
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Lih Lin
Electrical Engineering
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Research Interests
Nano-photonic waveguides by self-assembly
Optical manipulation of micro- and nano-objects
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Christine Luscombe
Materials Science and Engineering
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Research Interests
Professor Luscombe's research focuses on the design, synthesis, and applications of functional macromolecules. The group aims to develop new methods for making semiconducting polymers and to create new polymers with improved light absorption, charge transport, and stability.
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Alexander Mamishev
Electrical Engineering
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Research Interests
The goal of our research is to create new sensor and automation technology applications in such fields as non-destructive testing, power engineering, and manufacturing control using latest advances in signal processing, robotics, and communications. We are particularly interested in developing energy-efficient electrohydrodynamic air movers and using dielectric spectroscopy for non-destructive testing and forensics.
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David Masiello
Chemistry
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Research Interests
Professor Masiello's research focuses on the theoretical and numerical description of nanoscale light-matter interactions. This is accomplished by blending together the quantum mechanics of molecular radiators with the continuum electrodynamics of their nanoscopic environment. Surface-plasmon-supporting environments are often of considerable interest to us, as are the effects of their extreme electromagnetic near-fields upon molecular-electronic structure and energetics. Collaborations with experimental groups both at UW and at other US universities are of key importance to our work.
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René Overney
Chemical Engineering
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Research Interests
Research in Overney's Lab focuses on obtaining a fundamental understanding of material functionalities involving nano-confined complex molecular systems. We are particularly interested in i) identifying basic internal and external constraints that are responsible for "unique" material and transport properties, and ii) applying knowledge of molecular- and nano-constraints to material engineering in a rational fashion, with focus on the molecular building blocks, their subunits, and their temporal and spatial mobilities.
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Gerald Pollack
Bioengineering
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Research Interests
Water has three phases - gas, liquid and solid; but recent findings from our laboratory imply the presence of a fourth phase that occurs at interfaces. This phase is surprisingly extensive. Its presence may have profound implication for chemistry, physics and biology and we are actively considering all of these. Cell biology in particular considers water as a mere background carrier of the more important molecules of life. However, it appears that water is a central player and we are investigating just how.
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Jonathan Posner
Mechanical Engineering
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Research Interests
The Posner Research Group's focus is micro- and nano scale transport physics at the interface of chemistry, materials, & biology. Specific research topics include microfluidic and nanofluidic devices, colloidal science and interactions at fluid and solid interfaces, synthetic nanomotors, environmental and health impact of engineered nanomaterials, electrokinetics, low Reynolds number fluid instabilities, and fuel cells.
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Danilo Pozzo
Chemical Engineering
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Research Interests
Our research focuses on understanding and controlling self-assembly processes in dispersed colloidal, polymeric and nanoparticle systems. This fundamental knowledge allows for manipulation of material properties for applications in solar energy, nanomedicine, separations and advanced coatings amongst others. We also develop in-situ neutron and x-ray scattering techniques to formulate structure-property relationships under realistic processing and use conditions.
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Suzie Pun
Bioengineering
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Research Interests
Research in the Pun Group focuses on advancing macromolecule drug delivery technology by developing materials that overcome transport limitations in tissues and within cells. We are integrating techniques from engineering, chemistry, and cell biology to achieve this goal.
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Buddy D. Ratner
Chemical Engineering
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Research Interests
Medical devices and implants are engineered from specially designed materials, often referred to as biomaterials. Millions of devices and implants are used clinically in applications as diverse as blood vessel replacements, catheters, contact lenses, hip joints, ventricular assist devices and artificial kidneys. The biocompatibility of these prostheses is dictated by their surface properties and by the local mechanical environment they induce. In my research program, biomaterials are engineered to control biological interactions, synthesized, characterized and observed during interaction with biological systems.
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Daniel Ratner
Bioengineering
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Research Interests
The Ratner Laboratory's focus includes the development of synthetic and biophysical tools to analyze glycan-dependent interactions at the surface of cells, tissues, and biomaterials. Leveraging molecular engineering, carbohydrate chemistry, advanced surface modification and analysis, and label-free biosensing technologies, Professor Ratner aims to unravel the roles played by carbohydrates and glycoconjugates in biological systems and apply this knowledge to engineer new molecular diagnostics and therapeutics.
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Marco Rolandi
Materials Science and Engineering
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Research Interests
Research in the Rolandi lab is focused on understanding the charge transport properties in biological, organic, and inorganic nanomaterials to enable the design of nanodevices with practical applications. Our work relies on novel schemes that afford a precise control of the position, size, and shape of the building blocks and their assembly into systems with well defined properties. Fabrication strategies include chemical and biological self assembly, semiconductor nano/micromanufacturing techniques, and AFM lithography.
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Ram Samudrala
Microbiology
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Research Interests
Design of peptides and proteins with specific functionalities.
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Mehmet Sarikaya
Materials Science and Engineering
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Research Interests
By merging recent advances in molecular biology and genetics with state-of-the-art engineering and characterization from the physical sciences, our goal is to shift the biomimetic materials science paradigm from imitating Nature to designing and engineering natural materials to perform artificial functions. In this Center, we combine Nature's proven molecular tools with synthetic nanoscale constructs to make molecular biomimetics a full-fledged methodology. To this end, we have assembled a multidisciplinary team with expertise in diverse and synergistic areas ranging from molecular biology and chemistry to materials sciences and engineering.
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Michael Schick
Physics
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Research Interests
Membrane fusion, raft formation in membranes, self-assembly of polymer systems, defects
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Daniel Schwartz
Chemical Engineering
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Research Interests
The formation and function of electrochemical materials and interfaces are critically affected by molecular adsorption and templating. Our group explores the use of engineered proteins as modifiers of nucleation and growth, as well as orchestrators of hierarchical structures. In separate efforts, we also explore innovative methods to convert waste materials, especially lignocellulosic feedstocks, into value added products.
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Eric Seibel
Mechanical Engineering
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Research Interests
Optical tools for Nanotechnology Development with special emphasis for early cancer detection and treatment.
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Amy Shen
Mechanical Engineering
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Research Interests
My research program develops novel approaches in microfluidics to address complex and interdisciplinary questions at the interface of biology, chemistry and engineering. In particular, we couple hydrodynamics of self assembly fluids and external fields for applications in biosensor, single cell analysis, molecule assays, and novel hierarchically structured materials synthesis.
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Nathan Sniadecki
Mechanical Engineering
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Research Interests
Our lab investigates how cells are influenced by mechanical interactions at the micro and nanoscale. To pursue these goals, we are developing new tools -micro- and nano-devices, quantitative image analysis, and computational models - that we use to understand the underpinnings of biomechanics and mechanobiology. The greater impact of our work is to delineate how cell mechanics affect cardiovascular disease and cancer in order to catalyze new strategies for their treatment. By working at the intersection of mechanics and biology, we are increasing understanding of the theories of soft, active, and multifunctional materials.
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Patrick Stayton
Bioengineering
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Research Interests
Our group is interested in elucidating the fundamental mechanisms of biomolecular recognition and applying the unique capabilities of biological molecules to biotechnologies. We would like to bridge the gap between understanding molecular structure-function relationships, and to be able to utilize proteins/peptides/DNA for in vivo drug therapies, bioseparations, diagnostics, and biomaterial development.
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Wendy Thomas
Bioengineering
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Research Interests
The Thomas lab studies regulated adhesive proteins. While we study protein allostery in general, we are particularly interested in mechanical regulation. A main interest is in "catch bonds" that are activated to bind by tensile mechanical force. In particular, we study mechanical regulation of proteins involved in bacterial infection and thrombosis. We also engineer smart regulated adhesives. In our "actibodies" project, we design activatable, antibody-like recognition proteins. In our "biocatch adhesion" project, we integrate catch bonds into adhesives that will allow medical robots to catch human tissue under force, and then release it, like nanoscale locking seatbelts.
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Beth A. Traxler
Microbiology
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Research Interests
The research in Dr. Traxler's laboratory focuses on the genetic and biochemical analysis of protein folding and function. Recently, the lab has been involved in the development of materials for nanotechnology. Different proteins characterized in the lab's genetic analyses are being engineered by the addition of polypeptide sequences that bind to various inorganic compounds. Those inorganic compounds can be arranged in predictable structures, based on the self-assembly properties of the substrate proteins. Examples include using different DNA binding proteins to organize inorganic nanoparticles along a DNA guide.
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Pedro Verdugo
Bioengineering
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Research Interests
The Verdugo Lab works on processes whereby macromolecules assemble forming nanostructures have significant implications for understanding of questions ranging from marine polymer self-assembly in the ocean, to the formation of networks inside the cell, or the development of new drug delivery vehicles or vaccine preservation in medicine by caging them inside condensed block copolymer nano networks .
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Oscar E. Vilches
Physics
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Research Interests
Vilches's research is done in collaboration with Professor David Cobden and his students, focuses on the physisorption of rare gases and simple molecules on individual and bundled single wall carbon nanotubes. My interests focus on the lighter elements and molecules, where quantum effects show up. The atoms/molecules studied are the stable isotopes of helium and the stable molecules formed by hydrogen. Research is done at low temperatures, from the liquid helium range (below 4.2 K) to room temperature using liquid helium and nitrogen cryostats and mechanical cryogenic coolers. On single nanotubes, the measurement techniques used are resonance frequency of suspended nanotubes as a function of temperature, gas and equilibrium vapor pressure which determine the amount of mass adsorbed, and electrical conductance measurements as a function of mass adsorbed. On carbon nanotube bundles, the current technique used is adsorption isotherms (amount of gas on surface as a function of temperature and pressure). For detailed description of the single nanotube program and recent published papers please go to Prof. Cobden's website.
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Linda Wordeman
Physiology and Biophysics
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Research Interests
We use high resolution live imaging and total internal reflection microscopy to study molecular motors and their role in mitotic spindle assembly and chromosome movement. At the single molecule level we evaluate motor control of dynamic microtubule assembly and disassembly. Of special interest are the forces driving oscillatory chromosome movement, mitotic spindle assembly and mitotic spindle orientation in live cells. Finally, we are interested in the advection of motors in live cells. In other words, how the kinetic parameters of single microtubule motors influences their translocation, distribution and function in cells and we are interested in modeling this activity in silico.
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Paul Yager
Bioengineering
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Research Interests
Microfluidic devices for chemical and biochemical measurement and analysis; point-of-care diagnostic instruments; global health
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Miqin Zhang
Materials Science and Engineering
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Research Interests
Nanomaterials, nanoparticle tagging,
cell signalling, protein patterning,
nanofilter, drug delivery
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Shanrong Zhang
Radiology
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Research Interests
MRI, molecular imaging, nanoparticle, contrast agent
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