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"Foresight Institute - Dr. David Baker of the University of Washington, Department of Biochemistry, and Dr. Brian Kuhlman, of the University of North Carolina, Dept of Biochemistry and Biophysics, received the theory prize for their development of RosettaDesign, a program that has a high success rate in designing stable protein structures with a specified backbone folding structure. Their work includes the design of the first protein to be constructed with a backbone fold not observed in nature; in experimental testing, the novel backbone structure was found to be extremely stable and to match the predicted structure with atomic-level accuracy.
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