nemhauser lab
department of biology
university of washington
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Photomorphogenesis. Light shapes the seedling developmental program through modulation of a network composed of proteins, nucleic acids and small molecule hormones.
Life is hard. Among the many challenges of life at the cellular scale is how to gather and respond to information about an ever-shifting environment. One solution to this challenge is the evolution of mechanisms to convert information gathered by cellular receptors—which act like antennae to monitor the environment—into chemical signals. These chemical signals can then be translated by networks of interacting molecular factors into changes in cell growth or identity. The Nemhauser Lab investigates how the architecture and dynamics of signaling networks allow for the effective processing of information, and how plants tune these networks to optimize their morphology for a given environment. Our recent work has drawn from molecular genetics, genomics, physiology and synthetic biology to build new tools to study signaling dynamics and to apply these tools to a variety of fundamental questions in cell and developmental biology. Specifically, we are: