Contact Information:
University of Washington
Division of Nephrology
Box 356521
1959 NE Pacific St.
BB1257
Seattle, WA 98195
Phone: (206) 543-3792
Fax: (206) 598-2105
rdrvsula@u.washington.edu
Education and Training:
Nephrology Fellowship (1999-2003)
University of Washington
Seattle, TX
Chief Medical Resident (1999)
West Roxbury VA Hospital
West Roxbury, MA
Medicine Residency
(1996-99)
Beth Israel Hospital
Boston, MA
Medical School (1992-96)
McGill University
Montreal, Quebec
Canada
Site of Practice:
University of Washington Medical Center
raghu durvasula, MD
Associate Professor of Medicine, Division of Nephrology
Associate Medical Director for Inpatient Care
Clinical Interests
- Pathogenesis and treatment of glomerular disease
- Progression of chronic kidney disease
Research Interests
- Podocyte injury in states of glomerular capillary hypertension
- Intra-renal renin-agiotensin system and progression of glomerular disease
- Pleiotropic effects of statins in podocyte disease
- Experimental models of glomerular disease
Current Research
- Effects of mechanical strain in mediating podocyte detachment through upregulation of the matricellular protein SPARC
- Activation of a local angiotensin system in podocytes as a result of the diabetic milieu
- Effects of rosuvostatin as a pro-survival factor for podocytes
- Establishing the podocyte as a direct target of glucocorticoid signaling
- Identifying B cell linker protein as a novel constituent of the slit diaphragm assembly
Selected Publications:
Pub Med provides a list of Dr. Durvasula's research publications.
Awards
- NIH/NIDDK K08 Mentored Career Development Award (07/2003-6/2008); project title: "STretch Inducted Podocyte Injury - Role of Glomerulosclerosis."
- DERC Pilot and Feasibility Award 8/2004 - 7/2007; project title: "Role of angiotensin in mediating podocyte injury in diabetic nephropathy."
- Astra Zeneca Investigator Initiated Study 8/2005 - 7/2007; project title: "Role of rosuvastatin in preventing podocyte injury: Implications for the stabilization of progressive renal insufficiency."
- American Heart Association Beginner Grant-In-Aid Award (07/2007 - 06/2009); project title: "The Role of BLNK in Modulating Podycte Response Following Injury."
- First Prize, Outstanding Basic Science Research, 2003. Nephrology Young Investigators Forum hosted by the National Kidney Foundation of Northern California. Abstract entitled: "Activation of a local tissue angiotensin system in podocytes by mechanical strain."
- Pfizer Inc. "Outstanding Abstract Award" for Nephrology Fellows Program at the American Society of Nephrology Annual Meeting, 2001. Abstract entitled: "Upregulation of SPARC and TGF-beta by mechanical stretch in cultured mouse podocytes."
National Responsibilities
- Invited Speaker, Podocyte Signaling Symposium, American Society of Nephrology Annual Meeting, 2007.
- Moderator and Abstract Reviewer, American Society of Nephrology Annual Meetings, 2005, 2006, 2007.
- Grant Reviewer, National Medical Research Council, Singapore, 2006.
- Ad hoc reviewer, Kidney International, Journal of the American Society of Nephrology, Hypertension, 2003-present.
- Member, Northwest Renal Society, 2000-present.