Durvasula

Contact Information:
University of Washington
Division of Nephrology
Box 356521
1959 NE Pacific St.
BB1257
Seattle, WA 98195
Phone: (206) 543-3792
Fax:  (206) 598-2105
rdrvsula@u.washington.edu

Education and Training:
Nephrology Fellowship (1999-2003)
University of Washington
Seattle, TX

Chief Medical Resident (1999)
West Roxbury VA Hospital
West Roxbury, MA

Medicine Residency
(1996-99)
Beth Israel Hospital
Boston, MA

Medical School (1992-96)
McGill University
Montreal, Quebec
Canada

Site of Practice:
University of Washington Medical Center

 

raghu durvasula, MD

Associate Professor of Medicine, Division of Nephrology
Associate Medical Director for Inpatient Care

Clinical Interests

  • Pathogenesis and treatment of glomerular disease
  • Progression of chronic kidney disease

Research Interests

  • Podocyte injury in states of glomerular capillary hypertension
  • Intra-renal renin-agiotensin system and progression of glomerular disease
  • Pleiotropic effects of statins in podocyte disease
  • Experimental models of glomerular disease

Current Research

  • Effects of mechanical strain in mediating podocyte detachment through upregulation of the matricellular protein SPARC
  • Activation of a local angiotensin system in podocytes as a result of the diabetic milieu
  • Effects of rosuvostatin as a pro-survival factor for podocytes
  • Establishing the podocyte as a direct target of glucocorticoid signaling
  • Identifying B cell linker protein as a novel constituent of the slit diaphragm assembly

Selected Publications:

Pub Med provides a list of Dr. Durvasula's research publications.

Awards

  • NIH/NIDDK K08 Mentored Career Development Award (07/2003-6/2008); project title: "STretch Inducted Podocyte Injury - Role of Glomerulosclerosis."
  • DERC Pilot and Feasibility Award 8/2004 - 7/2007; project title: "Role of angiotensin in mediating podocyte injury in diabetic nephropathy."
  • Astra Zeneca Investigator Initiated Study 8/2005 - 7/2007; project title: "Role of rosuvastatin in preventing podocyte injury: Implications for the stabilization of progressive renal insufficiency."
  • American Heart Association Beginner Grant-In-Aid Award (07/2007 - 06/2009); project title: "The Role of BLNK in Modulating Podycte Response Following Injury."
  • First Prize, Outstanding Basic Science Research, 2003. Nephrology Young Investigators Forum hosted by the National Kidney Foundation of Northern California. Abstract entitled: "Activation of a local tissue angiotensin system in podocytes by mechanical strain."
  • Pfizer Inc. "Outstanding Abstract Award" for Nephrology Fellows Program at the American Society of Nephrology Annual Meeting, 2001. Abstract entitled: "Upregulation of SPARC and TGF-beta by mechanical stretch in cultured mouse podocytes."

National Responsibilities

  • Invited Speaker, Podocyte Signaling Symposium, American Society of Nephrology Annual Meeting, 2007.
  • Moderator and Abstract Reviewer, American Society of Nephrology Annual Meetings, 2005, 2006, 2007.
  • Grant Reviewer, National Medical Research Council, Singapore, 2006.
  • Ad hoc reviewer, Kidney International, Journal of the American Society of Nephrology, Hypertension, 2003-present.
  • Member, Northwest Renal Society, 2000-present.

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