Graduate Program in Neuroscience

Jeff Rasmussen

Photo of Jeff Rasmussen

Office:

371 Life Science Building (LSB)

Phone:

206-616-7248

Email:

rasmuss@uw.edu

Dept.:

Assistant Professor, Department of Biology

Box:

351800

Neuroscience Focus Groups:

Cell and Molecular Neuroscience, Developmental Neurobiology, Disorders of the Nervous System
Lab Link

Research:

The Rasmussen lab uses zebrafish to gain molecular and cellular insights into neuronal plasticity, both during development and following injury. The skin is our largest sensory organ and is densely innervated by somatosensory nerve endings that sense pain and touch. Nerve regeneration is often incomplete following skin injury, and sensory loss is a major complication associated with diabetes and chemotherapy. Using the imaging advantages of the zebrafish system and novel remodeling assays developed in the lab, we have identified interactions between somatosensory nerve endings and several specialized cell types (including osteoblasts, resident macrophages, and mechanosensory cells) within the skin tissue environment. We are currently pursuing the following related projects:

(1) Control of nerve patterning during skin development
(2) Genomic and cellular analysis of nerve regrowth following injury
(3) Development, regeneration, and function of mechanosensory cells