Gabe J. Murphy
Dept.: Associate Investigator, Allen Institute for Brain Science Affiliate Assistant Professor of Physiology and Biophysics, University of Washington
Neuroscience Focus Groups: Excitable Membranes and Synaptic Transmission; Neural Circuits; Sensory Systems
We characterize the selectivity with which cortical and subcortical neurons respond to visual stimuli and the degree to which those responses vary as a function of behavioral state and/or task. Parallel efforts characterize the physiological properties that underlie neuronal response properties – i.e., neurons’ intrinsic biophysical characteristics, the probability and specificity with which they are connected to one another, and the strength and dynamics of signaling between synaptically-coupled neurons. This insight, and assaying the effects of manipulating signals within and/or between neurons, enables us to both form and test hypotheses about how the structure of the nervous system gives rise to its function.