Graduate Program in Neuroscience

Jobs

11/16/2018

Inhouse Consulting- Global Graduate Program US Based:

Finishing or recently completed grad school and ready to launch your industry career? The US hub of Inhouse Consulting at Merck KGaA, Darmstadt, Germany is hiring team players with a global mindset to tackle science & technology business projects.

Inhouse Consulting is the internal management consulting department supporting the global businesses of Merck KGaA, Darmstadt, Germany. Our team of over 80 consultants and associates develops and implements local and global strategies for senior executives across all our business sectors: healthcare (EMD Serono), life science (MilliporeSigma) and performance materials (EMD Performance Materials). Our US offices are in the Greater Boston Area (Burlington and Rockland), while our Global Headquarters are located in Darmstadt, Germany. Our offices in Singapore and Shanghai serve clients in Asia Pacific.

Your Role:

Ideal candidates for the Global Graduate Program are early in their careers, enjoy working on teams, and have a global mindset. During the 24-month program, associates will experience a mix of strategic management consulting projects as well as functional rotations in the pharmaceutical, life science and performance materials industries. During the program, you will work out of our headquarters in Darmstadt, Germany for up to four months.  You may have other opportunities to be based across the US or internationally, depending on projects.

Associates will also participate in targeted professional trainings and our internal coaching program to continuously improve their technical expertise and business acumen.

Following successful completion of the Global Graduate Program, associates will move on to challenging and exciting positions across the company.

Who you are: 

  • Master’s degree or PhD in business, science and/or engineering
  • Must have demonstrated interest in business through coursework, professional experience, or internships
  • Strong analytical and strategic thinking skills
  • Proactive and self-motivated mindset
  • Outstanding communication and team-working skills
  • Excellent verbal and written English (additional language(s) a plus)
  • Mastery of MS Office (especially Excel and PowerPoint)
  • Flexibility and willingness to live and work from our headquarters in Darmstadt, Germany for up to 4 months
  • Applicants should be prepared for behavioral and consulting case interviews

Target Start Date: May/June 2019

Apply here: https://lnkd.in/eqcbiMT

Find out more on LinkedIn: https://www.linkedin.com/feed/update/urn:li:activity:6448882746390568960/

11/7/2018

Full-time Non-Tenure Track Senior Neuroscience Lecturer- College of Arts and Sciences: Natural Sciences: Interdisciplinary Neuroscience at Vanderbilt University (Nashville, TN)

Open Date
Oct 29, 2018
Description
The Interdisciplinary Neuroscience Program for Undergraduates in the College of Arts and Sciences at Vanderbilt University invites applications for a senior lecturer to teach undergraduate classes in neuroscience. This position is a full-time, non-tenure track appointment for an initial three-year contract with the possibility of subsequent renewal, conditional upon performance. Candidates must have earned a doctorate in a field of relevance, such as neuroscience, biological science, pharmacology or psychology. Successful candidates must have experience teaching in a higher education setting and must be able to provide evidence of excellence in teaching. We are particularly interested in individuals who can teach topics related to cellular and molecular neuroscience.
Additional information about the Interdisciplinary Neuroscience Program is available at https://as.vanderbilt.edu/neuroscience/. Please contact search committee chair, David Zald, Ph.D. (david.zald@vanderbilt.edu) for questions.
Qualifications
The Neuroscience program provides a premed curriculum with an emphasis on understanding the brain at multiple levels of analysis and is committed to engaging all students in immersive research experiences. The program involves faculty from multiple departments, including Biological Sciences and Psychology, as well as departments within the Vanderbilt School of Medicine. As such, successful candidates will need to be able to work collaboratively in a diverse academic environment. In addition to teaching responsibilities, senior lecturers are expected to participate in advising of Neuroscience majors and minors and may be asked to help coordinate immersive research experiences.
Application instructions are available at

11/7/2018

Assistant Professor Position (Neurobiology) – Biology Department at Adelphi University (Garden City, N.Y.) (Long Island)

JOB SUMMARY: Adelphi University invites applications for a tenure-track position in neurobiology to begin fall 2019. The successful applicant will join an active, engaged, and collegial department spanning all areas of biology as well as an exciting new interdisciplinary neuroscience program with the Derner School of Psychology. Opportunities for collaboration exist within the university as well as in the NY metropolitan area. For more information about the department, visit http://biology.adelphi.edu/.

RESPONSIBILITIES:

  1. Teaching undergraduate and graduate neurobiology, human anatomy & physiology and additional specialty courses for upper-level undergraduates and master’s students in the area of expertise.
  2. Candidates who use computational methods are encouraged to apply.
  3. Commitment to teaching students from diverse cultural backgrounds and excellent potential as a teacher.
  4. Plus a record of significant research accomplishment and the potential to develop a fundable independent research program involving undergraduate and master’s students.

QUALIFICATIONS:

  1. Ph.D in Biology or a closely related field is required.
  2. Postdoctoral experience is highly preferred.

APPLICATION:

  1. Applicants must upload their application online and submit the following (merged into one document): cover letter, CV, statement of teaching interests and philosophy, statement of research background and interests, and the names and contact information for 3 references.
  2. Deadline for applications: November 19, 2018.

DIVERSITY: Adelphi University is an equal opportunity/affirmative action employer committed to building a diverse workforce and strongly encourages applications from women, under-represented groups, members of the LGBT community, people with disabilities and veterans.

10/12/2018

PostDoctoral Fellow Position (Behavioral neuroendocrinology and circadian rhythms) – Oregon Health and Science University (Portland, Oregon)

The Butler Lab in the Oregon Institute of Occupational Health Sciences and
Department of Behavioral Neuroscience is seeking a postdoctoral fellow to study
sex differences in the circadian clock with a focus on the mechanistic role of the
androgen receptor. This position is supported by an NIH grant funded through 2023.
The work will involve electrophysiology of identified neurons in the suprachiasmatic
nucleus (SCN), imaging of clock genes in organotypic slice cultures, and
pharmacogenetic manipulations of behavior.

Applicants should have a Ph.D. in biology or neuroscience. Experience with
electrophysiology, tissue culture, or animal behavior will be an advantage but not a
requirement. The successful applicant will work closely with Matthew Butler (PI) and
Chuck Allen (Co-I) and will join a community at OHSU with strengths in circadian
and sleep biology in animal models and humans.

Research fellows are strongly supported in their professional development by a
mentoring team that provides guidance on career trajectory. Duties include animal
and bench experiments, data analysis, and writing and presenting the results.
Salary and rank are commensurate with education, skills, and experience.

For more information and to apply online visit www.ohsujobs.com, reference
IRC69708, or email Matthew Butler: butlema@ohsu.edu.
Please upload a letter of introduction, CV, and a list of 3 professional
references. For, more information, please see:
https://tinyurl.com/Matt-Butler-OHSU

10/12/2018

PostDoctoral Research Positions – Rutgers 

Post-doctoral openings are available in Dr. Victoria Abraira’s lab in the W. M. Keck Center for Collaborative Neuroscience at Rutgers University. Dr. Abraira’s research combines the power of mouse molecular genetics, animal behavior, electrophysiology, and high-resolution imaging to map and test the functions of specific neuronal circuits. Our goal is to carefully dissect the somatosensory system, in particular the sense of touch, to understand its contributions to health and disease

We are seeking self-motivated individuals with a strong commitment to neuroscience research. Candidates must have a Ph.D. in neurobiology, cell/molecular biology, or related field with one or more first author publications in internationally recognized peer-reviewed journals. Researchers with experience in electrophysiology/patch clamp recordings and/or mouse behavior are especially encouraged to apply. This position requires experience and willingness to work with mice. Salary will be negotiable, highly competitive, and commensurate with experience.

Our lab is both physically and thematically embedded within the Spinal Cord Injury Project at the Keck Center for Collaborative Neuroscience. The center includes four full time staff – two lab managers, an animal care/histology technician, and an imaging specialist – well trained in spinal cord neurobiology/spinal cord injury models to help carry out your project. In addition, Rutgers presents a vibrant research community, with $700 million in annual research and development expenditures. Successful candidates will benefit from an interactive and supportive neuroscience community that spans five Rutgers campuses, two local hospitals, and two medical schools; with abundant seminars, symposia and collaborations offering exposure to new ideas, cutting-edge techniques and career development. Rutgers is also a diverse campus with direct access to New York City, Philadelphia and Baltimore/Washington DC – all rich in career opportunities spanning academia, industry, and education. If interested, please formally apply through our website (abrairalab.org/openings) If you have any questions, please email Dr. Victoria Abraira (victoria.abraira@rutgers.edu).

10/09/2018

PostDoctoral Research Position- Johns Hopkins University, School of Medicine (Baltimore, Maryland)

The David Linden lab at Johns Hopkins University School of Medicine is seeking a curious and self-motivated postdoctoral researcher to investigate how the brain learns to anticipate neural activity and direct local bloodflow in advance of such activity.  These experiments involve extracellular recording and 2-photon imaging of the neurovasculature at subcellular resolution in the alert mouse.  Candidates should have some form of in vivo imaging or recording experience in animal models and should be comfortable with image analysis and coding.  Please send a cover letter and CV that lists at least 2 references to dlinden@jhmi.edu

10/01/2018

Assistant Professor in NueroBiology Position- University of Wisconsin-Madison (Madison, Wisconsin)

We seek a candidate to develop an internationally recognized research program focused on neurobiology at the University of Wisconsin-Madison. We are eager to attract candidates who study neuroscience at the molecular, cellular, or circuitry levels. Candidates with expertise in state-of-the-art approaches are encouraged to apply. We welcome applications from candidates using a range of experimental models, including non-mammalian, invertebrate or cell culture systems. Our goal is to hire an outstanding individual with broad research interests, promise for intellectual growth, and an ability to interact with an interdisciplinary and collaborative intellectual community. Candidates who can contribute to our goal to increase diversity are encouraged to identify their strengths and experience in this area. The successful candidate will join a world-class academic institution that encourages, values, and supports interdisciplinary basic and clinical research, and attracts scholars and students from around the world.

The position is based in the Department of Integrative Biology, which has 19 regular faculty members and 56 graduate students, drawn from multiple interdepartmental graduate programs on campus. The department brings together faculty and research programs that span a wide range of interests, including behavioral neuroscience, developmental and cellular neuroscience, cell biology, developmental biology, animal behavior, ecology and evolution. It offers a stimulating research environment as well as opportunities for collaborative research in other departments. Located at the nexus of four beautiful lakes, Madison, the state capital, consistently ranks among the top American cities for its quality of life.

Duties: Successful candidate will be expected to contribute to the teaching, research, and service missions of the Department of Integrative Biology. Teaching at the undergraduate and graduate levels is required, as is mentoring the research of undergraduate and graduate students. Candidate will be expected to engage in scholarly research in areas of specialization leading to scholarly publications at the national and international levels. Candidate will be required to perform university and professional service as appropriate.

Please visit: University of Wisconsin to apply

10/01/2018

two (2) Postdoc Positions- Australian National University, Neurophysiology lab (Canberra, Australia)

Cellular neurophysiology of the olfactory cortex

Two postdoctoral positions are available at the Australian National University to conduct fundamental research on how olfactory information is processed by the primary olfactory (piriform) cortex.  Projects include the use of an endoscope to image olfactory plasticity in behaving mice, and using in vivo patch clamping and 2-photon microscopy to study dendritic electrogenesis.

You will join the dynamic, collaborative research environment provided by the Eccles Institute of Neuroscience, which is part of the John Curtin School of Medical Research, one of the world’s top medical research institutes.

You must have a PhD in neuroscience, a strong record of research achievement, and demonstrated experience in the key techniques of cellular neurophysiology.  Both positions are for up to 3 years in the first instance, with the possibility of extension.  The salary is A$71,509 – A$90,215 p.a. plus 17% superannuation and 4 weeks of paid annual leave.

For further information, please contact Prof John Bekkers <John.Bekkers@anu.edu.au>.

To apply, go to <http://jobs.anu.edu.au> and search for “526258” or “olfaction”.  Application deadline: October 1st, 2018 [If the imminent deadline is a problem, please let people know that they can write to John Bekkers direct for special consideration.]

09/18/2018

Scientist I– Neuroanatomy and Data Analysis (The Allen Institute; Seattle)

Our mission at the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Our research goals include generating and analyzing large-scale anatomical imaging data from Alzheimer’s disease mouse models. We are seeking a Scientist to join the Neuroanatomy team and to help with image processing and data analysis related to our whole-brain projection mapping projects.

As a member of this team, the Scientist will perform computational analyses aimed at understanding the organization of whole brain connectivity patterns and pathology in aging and diseased brains. She/he should have experience working with voxel-based image data, solid programming skills, and a strong background in mathematics and statistics. The Scientist will also be responsible for generating data visualizations, establishing signal detection metrics for primary data, generating computational models, performing statistical analysis on large datasets, and assisting with analysis and visualization of single cell RNA sequencing data.

For more information on this position, please visit: Scientist-Neuroanatomy and Data Analysis

 

Postdoc Fellow- University of Maryland (Maryland)

PhD students who are 12-18 months from graduating

Start date: September 1, 2019 or later; open until filled

Position Summary:  We are looking for one or more postdoctoral fellows to study the organization and activation of neural circuits supporting perceptual learning in Mongolian gerbils. Successful applicants will use a variety of techniques, such as wireless multichannel electrophysiology, targeted pharmacological brain infusions and optogenetics to measure and manipulate neural activity in awake, freely-moving animals engaged in behavioral auditory detection tasks. Candidates will be highly involved in all aspects of the research, from design to publication, and will additionally have the opportunity to mentor graduate and undergraduate students.

For more information visit: The Caras Lab 

08/06/2018

Assistant Professor Position in Psychology (Specializing in Neuroscience)– Whitman College, WA

There is a currently a tenure track assistant professor position specializing in Neuroscience available for the upcoming year. Applications are due by September 27, 2018 and a PhD is required. For more information, please see the original post here: Assistant Professor Position

 

Science Officer Positions– Ripple Effect (Maryland)

Ripple Effect Communications, Inc is a women-owned small business that does biomedical contracting for the federal government, and hires scientists who are interested in alternative careers. Ripple Effect currently has two openings for scientists with a neuroscience background.

Ripple Effect is looking to hire Science Officers to provide grants management support to CDMRP (Congressionally Directed Medical Research Programs). We are looking for applicants with backgrounds in biomedical research, particularly in neuroscience research. We are also looking for “generalists” who can work in any biomedical field. Positions are based on-site at CDMRP in Frederick, MD. A more detailed job posting is available here: Science Officer Position

All available positions are on the the Ripple Effect website: https://ripple-effect-communications-inc.workable.com/.

08/03/2018

 Post-Doc Position (research associate)- University College London (UCL) 

The project will record place cells in dorsal CA1 and cells in prelimbic/infralimbic cortex while rats perform navigation tasks in hierarchical environments. As part of the project, in parallel, a post-doc in Chris Summerfield’s Lab in Oxford will use a VR version of the rat task to test humans during fMRI. In addition, the data from rats and humans will be integrated with
modelling done by a post-doc in Giovanni Pezzulo’s lab in Rome.

Key Requirements 
Applicants must hold a PhD, or have submitted their thesis in Neuroscience/Psychology and have experience of neural recording in animals. The ability to work as part of a research team is essential, as is the ability to problem-solve in a technical setting. Computer skills include Matlab programming are desirable. Particular importance will be given to one or more of the following: experience with animal behavior, high level analytic skills, experience with multi-electrode recording or experience with computational modeling of navigation behavior.

Further Details

Applicants will be interviewed in September and the start date is in October. For more information please see: Research associate- Reference #1740251

 

07/25/2018

 

Technician  Position – University of Washington (Lattemann’s Lab)

There will be a technician position available in Dianne Lattemann’s lab at the VAPSHCS starting approximately October 1st.
Full time or part time and is negotiable ad will be discussed.
Skill Requirements: Basic rat handling and measurement skills. Brain surgery/cannulation skills desirable but training can be provided. Some tissue- and blood-sample processing skills or experience required.
Position will also require contributions to lbasic ab logistical activities (e.g., placing orders, regulatory compliances).

Reply to: Doamme Lattemann, latte@uw.edu

 

07/13/2018

Postdoctoral Position – University of Pittsburgh

A postdoctoral position is open for highly motivated candidates in the laboratory of Dr. Bokai Zhu at the Aging Institute of University of Pittsburgh School of Medicine. The Zhu lab recently discovered a cell-autonomous mammalian 12h-clock that runs independently from the circadian clock to regulate 12h oscillations of gene expression and metabolism (Zhu et al., Cell Metabolism, 2017, Zhu et al., JES, 2018). The Zhu lab is currently investigating the regulation as well as the physiological/pathological functions of the 12h-clock, with an emphasis on its roles in maintaining hepatic metabolic homeostasis and preventing aging-associated diseases. A combination of state-of-the-art computational, biochemical, genetic, cellular, imaging and genomic approaches is currently utilized in the lab. For a detailed description of the research performed in Zhu lab, please visit http://www.bzhulab.com.

The search is primarily targeted towards scientists who recently finished their PhD. Start date is after Sep 1st, 2018 and flexible. Researchers with a passion in systemic and quantitative chronobiology, transcriptional regulation of metabolism, and ER and mitochondria biology, regardless of their training background, are welcome to apply. Expertise in any of the following areas is highly valued though not required:

* In vivo mouse circadian and hepatic metabolism techniques

* Molecular biology, biochemistry and the field of regulation of gene expression

* Bioinformatics expertise in the analysis of NGS datasets such as RNA-Seq, ChIP-Seq and GRO-Seq

* Imaging-based cell biology techniques

Pitt med is a national leader in biomedical research. University of Pittsburgh School of Medicine is currently ranked 14th in the category of research by U.S. News and is separately ranked 17th in the Academic Ranking of World Universities list of best medical schools in the world. The medical school’s NIH funding level also ranks fifth in the nation.

To apply, please send a cover letter describing your past training, research interests and career goals, a detailed CV and contact information of three referees to Dr. Bokai Zhu at BZHU@pitt.edu.

 

06/29/2018

DHHS Research Fellow – Computational Biology Core

The National Institute on Aging (NIA), Intramural Research Program (IRP), a major research component of the National Institutes of Health (NIH) and the Department of Health and Human Services (DHHS), is recruiting a Research Fellow (RF) for the newly created Computational Biology Core, located in the Laboratory of Genetics and Genomics (LGG), NIA, NIH, Baltimore, MD.  The RF will work with the Computational Biology Core Head and NIA/IRP Principal Investigators to convert information to knowledge in projects utilizing ‘omics’ approaches, and in training NIA staff in computational approaches through classroom instruction.  The incumbent will analyze and integrate genomics and proteomics data as well as other ‘omics’ data.  Excellent interpersonal skills and a collaborative style are required.

Eligible candidates must have a Ph.D. or M.D. (or M.D., Ph.D.) or equivalent degree in the Biomedical Sciences/Bio-Statistics/Computer Science/Engineering, and have broad experience in computational biology, bioinformatics, genomics, aging, and age-related diseases documented by publications.  Experience in teaching, managing large datasets and computational tasks, and working in a Linux environment are essential.  Expertise in data analysis using a wide array of modern, open-source bioinformatics tools and scripting languages (e.g., Bash, Perl, Python and, R/Bioconductor) and strong statistical knowledge are required.

The successful candidate will have a strong background in multiple sequencing platforms as well as methods such as RNA-seq, ChIP-seq, CLIP-seq, nucleosome-seq, whole-genome sequencing, single-cell sequencing, and bisulfite sequencing.  The ability to perform cross-platform data integration is required, and knowledge of the above-mentioned methods is highly desirable, in order to assist Principal Investigators throughout the NIA with designing, troubleshooting, and identifying strengths and drawbacks of platforms and methods.

Salary is commensurate with research experience and accomplishments, and a full Civil Service package of benefits (including retirement, health, life and long-term care insurance, Thrift Savings Plan participation, etc.) is available. All employees of the Federal Government are subject to the conflict-of-interest statutes and regulations, including the Standards of Ethical Conduct.  Additional information about LGG is available at the following website:https://www.irp.nia.nih.gov/branches/lgg/lgg.htm.

To apply, please send a cover letter, curriculum vitae, bibliography, research interests, and three letters of recommendation to: Jamie Hertzfelt, Intramural Program Specialist; Office of the Scientific Director, Vacancy #NIA-IRP-18-03, National Institute on Aging, NIH Biomedical Research Center, 251 Bayview Blvd., Suite 100, Room 04C232, Baltimore, Maryland 21224 or email niairpjobs@mail.nih.gov.  The first review of applications will begin on or about August 20, 2018, but applications will be accepted until the position is filled.

06/15/2018

Postdoc opportunity, with a target start date of Fall 2018 (flexible).
Kenway Louie, MD PhD                  
Center for Neural Science
New York University
http://www.cns.nyu.edu/~klouie/
We’re currently hiring a postdoctoral research fellow interested in studying the computational and neurophysiological basis of decision making in monkeys. This postdoc will be part of an NIH-funded project looking at canonical neural computations in value coding and their relationship to optimal choice behavior, with a particular focus on the relationship between statistical regularities in the environment and adaptive neural responses. The work will be supervised by myself and Paul Glimcher, and be conducted at the Center for Neural Science at New York University.
If you know of anyone who would be a good candidate, please let them know about this opportunity. We’re primarily looking for anyone with a good foundation in systems neuroscience and an interest in neural coding and decision making, though electrophysiology experience (of any sort) would be a plus. Interested candidates can either email me directly <klouie@cns.nyu.edu> or visit the application site at https://apply.interfolio.com/50154

05/08/2018

Postdoctoral Research Position Available

William A. Catterall

Department of Pharmacology and Neuroscience Program

University of Washington, Seattle, WA 98195-7280 USA

Sodium Channels and Dravet Syndrome, an Intractable Childhood Epilepsy

Genetically dominant loss-of-function mutations in the type-1 brain sodium channel NaV1.1 cause Dravet Syndrome, which includes intractable epilepsy, ataxia, sleep and circadian disorders, severe cognitive deficit, autistic-like behaviors, and frequent premature death. We developed a mouse model of Dravet Syndrome that recapitulates all of its features. We found that NaV1.1 channels are particularly important for electrical excitability of GABAergic interneurons and that all of the manifestations of this disease are caused by failure of firing of GABAergic interneurons and disinhibition of neural circuits.

Our current research is aimed at understanding the defects in neural circuits that lead to the different manifestations of Dravet Syndrome and at developing novel, science-based therapies. We are using the Cre-Lox method to mutate NaV1.1 in specific cell types and in specific anatomical regions. We record the functional effects of these gene deletions on neurons and neural circuits in brain slices using patch clamp and in whole animals using tetrodes. We are using optogenetics and gene editing to rescue the impaired firing of specific disease-relevant classes GABAergic neurons. We are testing novel pharmacological approaches that are based on our emerging understanding of the detailed pathophysiology of this disease.  We hope that our research will lead to new understanding and practical therapies for this devastating disease.

See Rubinsteiin, Brain 2015; Kaplan, PNAS 2017; Catterall, Current Opinion in Physiology 2018

Position Requirements

Basic molecular and cellular biology, whole-cell voltage clamp physiology, and brain slice recording are required.

Experience with in vivo recording and behavioral studies in rodents is valuable.

We seek enthusiastic well-trained neuroscientists who are excited about the opportunity to analyze a devastating neuropsychiatric disease at cellular, circuit, and systems levels and develop novel therapeutic approaches.

Please respond to wcatt@uw.edu

05/08/2018

Postdoctoral Research Position Available

William A. Catterall

Department of Pharmacology and Neuroscience Program

University of Washington, Seattle, WA 98195-7280 USA

Calcium Channel Regulation, Presynaptic Plasticity, and Spatial Learning and Memory

Presynaptic CaV2.1 channels initiate neurotransmission at synapses in the brain. They are regulated by binding of calmodulin to a bipartite regulatory site in the proximal C-terminal domain. During trains of stimuli, initial calcium binding to high-affinity EF hands 3 and 4 causes facilitation of the calcium current and subsequent calcium binding to low-affinity EF hands 1 and 2 causes inactivation. In cultured sympathetic neurons, transfected CaV2.1 channels induce short-term presynaptic plasticity that is blocked by the IM-AA mutation in their calmodulin regulatory site. We have developed an IM-AA mutant mouse line, in which presynaptic plasticity is impaired at hippocampal synapses. The deficit in presynaptic plasticity leads to altered excitation/inhibition ratio in hippocampal circuits, weakened long-term potentiation of synaptic transmission, and dramatically impaired spatial learning and memory.

Our current experiments are aimed at understanding how the IM-AA mutation impairs spatial learning and memory at the cellular, circuit, and systems levels. We will use molecular and cellular biology, whole-cell voltage clamp, and synaptic physiology to probe the underlying mechanisms for the effects of the IM-AA mutation on short-term synaptic plasticity and long-term potentiation at synapses in the hippocampus. We will study the input-output relationships of neural circuits in the hippocampal slice. We will use tetrodes and optical probes to record circuit functions of the hippocampus in vivo in awake, behaving mice, including studies of hippocampal sharp waves and sharp-wave ripples. Based on these results, we will develop realistic neural models for the changes in cellular and circuit function that impair spatial learning and memory in IM-AA mice.

See Nanou et al, PNAS 2016; J Neurosci 2018; Neuron 2018

Position Requirements

Basic molecular and cellular biology, whole-cell voltage clamp physiology, and brain slice recording are required.

Experience with in vivo electrophysiology and behavior in rodents is valuable.

We seek enthusiastic well-trained neuroscientists who are excited about the opportunity to study the mechanisms of synaptic plasticity, learning, and memory from calcium channel structure and function to neural circuits and behavior.

Please respond to wcatt@uw.edu

05/04/2018

Scientist and/or Sr. Research Associate Position – Kineta, Inc.

The open scientific position(s) will support the preclinical development of conopeptide-based therapeutics for treating neuropathic pain. The successful candidate will be responsible for the design, execution and interpretation of in vitro and in vivo experiments related to the characterization of lead compounds using electrophysiology and pharmacodynamic animal models. Hands on experience with technical methods utilized in nociception studies is required including familiarity with drug- and/or nerve injury-induced neuropathic pain, and behavioral testing including von Frey, Randal-Selitto, Hargreaves and cold plate tests. In addition, the successful candidate will participate in evaluating drug mechanism of action using in vitro and ex vivo assays.

Essential experience and skills —

Experience including whole blood and cell subtype isolation, cell culture and cell-line generation, immunohistochemistry, Luminex, FACS and ELISA, in vitro and in vivo electrophysiology are a plus. Good communication skills and ability to collaborate across multidisciplinary scientific discovery settings. The candidate will be required to work both independently and in a multidisciplinary team setting to ensure timely completion of studies and is expected to present experimental findings at internal meetings and through written reports. Good communication skills and ability to collaborate across multidisciplinary scientific discovery settings. A successful candidate will possess proven skills to adapt and quickly learn new techniques in a dynamic drug discovery environment. This person will be a highly motivated individual with excellent organizational skills. Independent thinking and excellent communications skills are desired.

Desired qualifications – 

  • Bachelors within >6 years of neuroscience working experience.
  • Master’s degree with >3 years of relevant neuroscience experience.
  • A Ph.D. with experience in the field of neuroscience required.
  • Strong experience in neuroscience and behavioral models
  • Ability to work in the vivarium.
  • Computer proficient (Windows), possess excellent written and oral communication skills.
  • Show attention to detail.
  • Experience working in a fast-paced research environment

Contact Kineta, Inc for more details – www.kinetabio.com

04/20/2018

Postdoctoral Position – Computational Modeling of Brain Networks

Stanford University’s Department of Psychiatry & Behavioral Sciences is seeking to hire a full time post-doctoral fellow for their Cognitive & Systems Neuroscience Laboratory. This lab is headed by Dr. Vinod Menon who has broad multidisciplinary expertise that spans several scientific disciplines and has published extensively on various aspects of human cognition and brain function.
 
Explore our lab website for more information: http://med.stanford.edu/scsnl.html.
Currently Available: The Stanford Cognitive and Systems Neuroscience Laboratory invites applications for a postdoctoralfellowship in computational modeling of human brain imaging data using deep neural networks. The successful candidate will be involved in a multidisciplinary project that seeks to develop novel computational frameworks for robust identification of neurobiological signatures of psychiatric and neurological disorders combining deep learning and convolution networks and dynamic brain circuit analyses with task and resting-state fMRI. Clinical disorders currently under investigation include autism, ADHD, anxiety and mood disorders, learning disabilities, schizophrenia, and Parkinson’s disease. We seek talented and highly-motivated individuals with a strong background in at least one of these areas: deep learning algorithms and optimization (theory and practical implementations); computational modeling, statistical inference, and machine learning, especially as applied to fMRI and MRI data. The candidate will have access to multiple large datasets and state-of-the-art computational resources, including HPCs and GPGPUs. Please email a CV, statement of research interests and relevant background, and have three letters of reference sent to Drs. Vinod Menon and Aarthi Padmanabhan at scsnl.stanford+postdoc@gmail.com