Molecular Basis of Drug Addiction
Pharmacology 534 - Autumn 2010
C Chavkin, N Stella, J Neumaier, and P Phillips - InstructorsThe class format starts with an introduction by the instructor followed by a discussion of the papers listed. Students are expected to have read the papers beforehand, and come to class prepared to discuss the methods, experimental design, and principal conclusion of the assigned papers. The course is designed to enhance the critical reading skills of the students and to familiarize the students with the strengths and limits of the key techniques in this research area.
| 9/30/10 3:30-5:30 PM | Introduction (Chavkin) | |
| 10/7/10 3:30-5:30 PM | Dopamine D2 receptors in addiction (Phillips) | |
| 10/14/10 3:30-5:30 PM | Endocannabinoid synthesis, signal transduction (Stella) | |
| 10/21/10 3:30-5:30 PM | Genetic approaches to identify addiction risk (Chavkin) | |
| 10/28/10 3:30-5:30 PM | Stress mechanisms underlying depression, anxiety disorders and addiction (Neumaier) | |
| 11/4/10 3:30-5:30 PM | Serotonin in mood (Neumaier) | |
| 11/10/10 3:30-5:30 PM | Recent advances in modeling addiction in animals and testing theories of addiction (Willuhn) | |
| 11/18/10 3:30-5:30 PM | Cannabinoid Receptor Signal Transduction (Stella) | |
| 11/23/10 | Addiction Risk factors for children (Skinner) | |
| 12/2/10 3:30-5:30 PM | Glutamate (last session) Tonic glutamate regulation in addiction (Phillips) | |
| 12/9/10 3:30-5:30 PM | TBN (Zweifel) | |
| 12/16/10 3:30-5:30 PM | Final Session (wrap up discussion of key concepts and future directions) |