UW Policy for the Use of Antibiotics in Laboratory Animals

UW Policy for the Use of Antibiotics in Laboratory Animals

Approved March 22, 2001    (Download) 

Background: The rationale for a policy on the use of antibiotics includes the following: 1) Oversight of antibiotics given to animals at the UW is the responsibility of the veterinary staff and the Institutional Animal Care and Use Committee (IACUC); 2) The use of antibiotics can be a complicating factor that alters research results; 3) Antibiotics can potentially be toxic to animals or produce nosocomial infections; 4) Prudence dictates the development of guidelines to prevent the development of antibiotic resistant microorganisms; 5) When the decision is made to use antibiotics, it is desirable to optimize therapeutic efficiency.

 

Policy: The use of antibiotics for treatment of clinical infections is only appropriate if prescribed by veterinary services. When animals with abnormalities are found, veterinary services should be notified so that affected animals can be evaluated and treatment prescribed. The drug, dose, frequency, and route of administration must be as prescribed.

The use of antibiotics for prophylaxis is only appropriate if prescribed by veterinary services and approved by the IACUC. If prophylactic antibiotics are to be administered as a part of a protocol, the drug, dose, frequency, and route of administration must be as prescribed. Specific policies are in effect for prophylactic antibiotic use in survival surgery and post-irradiation.