Michael G Gravett, MD
Professor and Director, Maternal-Fetal Medicine
Vice Chair, Department of Obstetrics and Gynecology

• MD degree
   (University of California, Los Angeles, 1977)
• Residency in Obstetrics and Gynecology
   (University of Washington, 1981)
• Senior Fellow, Infectious Disease, Immunology
   (University of Washington, 1981–82)
• Senior Fellow, Maternal-Fetal Medicine
   (University of Washington, 1982–83)

• Toll-Like Receptor Antagonism as a Potential Treatment for Preterm Labor
   (Co-Investigator/Mentor)
• New Model of Ascending Infection Related Preterm Birth
  (Co-Principal Investigator)
• Global Alliance for Prevention of Prematurity & Stillbirth

• Infectious Disease Society for Obstetrics and Gynecology
• American Sexually Transmitted Disease Association
• American Society for Microbiology
• Society for Maternal-Fetal Medicine
• Pacific Coast Obstetrical and Gynecological Society
• Society for Gynecologic Investigation
• Perinatal Research Society
• Infectious Disease Society for Obstetrics and Gynecology (President-elect)

Sadowsky DW, Adams KM, Gravett MG, Axthelm MK, Novy MJ. Preterm labor is induced by intraamniotic infusions of interleukin-1β and tumor necrosis factor-α but not by interleukin-6 or interleukin-8 in a non-human primate model. Am J Obstet Gynecol. in press.

Adams KM, Persing D, Novy MJ, Sadowsky DW, Gravett MG. Pre-treatment with Toll-like receptor 4 antagonist inhibits lipopolysaccharide-induced preterm uterine contractility, cytokines, and prostaglandins in rhesus monkeys. Reproductive Sciences 2008;15:121-127

Gravett MG, Adams KM, Sadowsky DW, Grosvenor AR, Witkin SS, Axthelm MK, Novy MJ. Immunomodulators plus antibiotics delay preterm delivery after experimental intra-amniotic infection in a nonhuman primate model. Am J Obstet Gynecol. 2007;197:518.e1-518.e8.

Gravett MG, Novy MJ, Thomas A, Schneider KA, Reddy AP, Dasari S, Jacob T, Lu X, Rodland M, Pereira L, Sadowsky DW, Roberts CT, Nagalla SR. Proteomic analysis of cervical-vaginal fluid: identification of novel biomarkers for detection of intra-amniotic infection. J Proteome Res. 2007;6:89-96.

Gravett MG, Novy MJ, Rosenfeld RG, Reddy AP, Haung J, Jacob T, Turner M, McCormack A, Lapidus JA, Hitti J, Eschenbach DA, Roberts CT, Nagalla SR. Diagnosis of intraamniotic infection by proteomic profiling and identification of novel biomarkers. JAMA 2004;292:462–469.

Sadowsky DW, Novy MJ, Witkin SS, Gravett MG. Dexamethasone or interleukin-10 blocks interleukin-1ß induced uterine contractions in pregnant rhesus monkeys. Am J Obstet Gynecol 2003;188:252–263.

Gravett MG, Hitti J, Hess DL, Eschenbach DA. Intrauterine infection and preterm delivery: evidence for activation of the fetal hypothalamic-pituitary-adrenal axis. Am J Obstet Gynecol 2000;182:1404–1413.

Gravett MG, Nelson HP, DeRouen T, et al. Independent association of bacterial vaginosis and Chlamydia trachomatis infection with adverse pregnancy outcome. JAMA 1986;256:1899–1903.

Gravett MG, Eschenbach DA, Hummel D, et al. Preterm labor associated with subclinical amniotic fluid infection and with bacterial vaginosis. Obstet & Gynecol 1985;67:229–237.