Adams Kristina Dept web

Kristina M Adams Waldorf, MD

Associate Professor

 
Joined UW Medicine:

7/1/02

Clinical Focus:

• Laparoscopic gynecologic surgery
• Abnormal uterine bleeding and fibroids
• Menopausal disorders
• Contraception for the medically complicated patient
• Pre-malignant gynecologic conditions/tumors
• Abnormal Pap smears/cervical dysplasia

Licensure:

Washington, 2001

Certification:

Obstetrics and Gynecology, 2004

Education:

• MD Degree
   (Mayo Medical School, 1998)
• Residency in Obstetrics and Gynecology
   (University of Washington, 2002)
• Women's Reproductive Health Research Career Development Scholar
   (University of Washington, July 1, 2002–Dec 21, 2006)
• Mentored Clinical Scientist Development Scholar
   (University of Washington, March 2007–March 2012)

Research Interests:

• Preterm labor
• Maternal-fetal immunology
• Maternal and fetal microchimerism

Current Research:

• GBS-Mediated In Utero Fetal Injury
• Eukaryotic-Type Signaling Mediates Two-Component Regulation of GBS Virulence
• Global Alliance for the Prevention of Prematurity and Stillbirth (GAPPS)

Memberships:

• American Congress of Obstetricians and Gynecologists
• Society for Gynecologic Investigation
• Fred Hutchinson Cancer Research

Selected Publications:

Adams KM, Lambert NC, Heimfeld S, Tylee TS, Pang JM, Erickson TD, Nelson JL. Male DNA in female donor apheresis and CD34-enriched products. Blood 2003;102(10):3845-7.

Adams KM, Nelson JL. Microchimerism: an investigative frontier in autoimmunity and transplantation. JAMA 2004;291(9):1127-1131.

Sadowsky DW, Adams KM, Gravett MG, Axthelm MK, Witkin SS, Novy MJ. Intraamniotic infusions of IL-1ß and TNF-a, but not IL-6 or IL-8, induce preterm labor in a non-human primate model. Am J Obstet Gynecol 2006;195:1578-89.

Adams KM, Lucas JL, Kapur RP, Stevens AM. LPS induces translocation of TLR4 in amniotic epithelium. Placenta 2007;28:477-81. PMCID: PMC3067058.

Gravett MG, Adams KM, Sadowsky DW, Witkin SS, Axthelm MK, Novy MJ. Immunomodulators plus antibiotics delay preterm delivery after experimental intraamniotic infection in a nonhuman primate model. Am J Obstet Gynecol 2007;197(5);518.e1-518.e8.

Adams Waldorf KM, Persing D, Novy MJ, Sadowsky DW, Gravett MG. Pretreatment with toll-like receptor 4 antagonist inhibits lipopolysaccharide-induced preterm uterine contractility, cytokines, and prostaglandins in rhesus monkeys. Repro Sci 2008;15(2);121-27. PMCID:PMC2774271.

Becher N, Adams Waldorf KM, Hein M, Uldbjerg N. The cervical mucus plug: Structured review of the literature. Acta Obstet Gynecol Scand 2009;88(5):502-13.

Adams Waldorf KM, Gammill H, Lucas J, Aydelotte T, Leisenring WM, Lambert NC, Nelson JL. Dynamic changes in fetal microchimerism in maternal peripheral blood mononuclear cells, CD4+ and CD8+ cells in normal pregnancy. Placenta 2010;31(7):589-94. PMCID:PMC2923456.

Chang J, Jain S, Carl DJ, Paolella L, Darveau RP, Gravett MG, Adams Waldorf KM. Differential host response to LPS variants in amniochorion and the TLR4/MD-2 system in Macaca nemestrina. Placenta 2010;31(9):811-17. PMCID:PMC2934902.

Grigsby PL, Novy MJ, Adams Waldorf KM, Sadowsky DW, Gravett MG. Choriodecidual inflammation: A harbinger of the preterm labor syndrome. Repro Sci 2010;17(1):85-94.

Taglauer ES, Adams Waldorf KM, Petroff MG. The hidden maternal-fetal interface: events involving the lymphoid organs in maternal-fetal tolerance. Int J Dev Biol 2010;54(2-3):421-30. PMCID:PMC2846427.

Adams Waldorf KM, Gravett MG, McAdams RM, Paolella LJ, Gough MG, Carl DJ, Bansal A, Liggitt HD, Kapur RP, Reitz FP, Rubens CE. Choriodecidual Group B streptococcal inoculation induces fetal lung injury without intra-amniotic infection and preterm labor in Macaca nemestrina. PLoS ONE 2011;6(12):e28972. PMCID: PMC3244436.

Gammill HS, Adams Waldorf KM, Aydelotte TM, Lucas J, Leisenring WM, Lambert NC, Nelson JL. Pregnancy, microchimerism and the maternal grandmother. PLoS ONE 2011;6(8):e24101. PMCID: PMC3166068.

McAdams RM, Vanderhoeven J, Beyer RP, Bammler TK, Farin FM, Liggitt HD, Kapur RP, Gravett MG, Rubens CE, Adams Waldorf KM. Choriodecidual infection downregulates angiogenesis and morphogenesis pathways in fetal lungs from Macaca nemestrina.  PLoS ONE 2012;7(10):e46863. PMCID:PMC3467273.

Whidbey C, Harrell MI, Burnside K, Ngo L, Becraft AK, Iyer LM, Aravind L, Hitti J, Adams Waldorf KM, Rajagopal L. A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta. J Exp Med 2013;210(6):1265-81.

Appointments & Practice Locations

Women's Health Care Center, Roosevelt (WHCC)
4245 Roosevelt Way NE, 4th Floor
Seattle, WA 98105-6920

Appointments:   206.598.5500