Cheng Edith dept web

Edith Y Cheng, MD, MS

Professor
Obstetrics Service Chief
Associate Division Director, Clinical Operations
Medical Director, Maternal and Infant Care Center
Medical Director, Prenatal Genetics and Fetal Therapy Program
Program Director, Prenatal Diagnosis and Treatment Program, Seattle Children's

 
Joined UW Medicine:

7/1/95

Clinical Focus:

Maternal-Fetal Medicine:
• Prenatal diagnosis
• Genetics
• Maternal cystic fibrosis
• Women/fetuses with genetic conditions

Licensure:

Washington, 1990

Certification:

• Genetic Counseling, 1982
• Medical Genetics, 1993, 2003, 2009
• Obstetrics and Gynecology, 1998
• Maternal-Fetal Medicine, 2000

Education:

• MS, Genetic Counseling
   (Sarah Lawrence College, 1979)
• MD Degree
   (University of Washington, 1987)
• Residency in Obstetrics and Gynecology
   (University of Washington, 1991)
• Fellowship in Medical Genetics
   (University of Washington, 1993)
• Fellowship in Maternal-Fetal Medicine
   (University of Washington, 1995)

Research Interests:

• Meiosis in human oogenesis

Memberships:

• American Society of Human Genetics
• American College of Medical Genetics
• American Congress of Obstetricians and Gynecologists
• Society for Maternal-Fetal Medicine
• American Society of Genetic Counselors

Honors:

• National Faculty Teaching Award, Dept of Ob/Gyn (2009)
• University of Washington Service Excellence Award (2006)

Selected Publications:

Rowsey R, Kashevarova, Murdoch B, Dickenson C, Woodruff T, Cheng E, Hunt P, Hassold T. Germline mosaicism does not explain the maternal age effect on trisomy. Am J Med Genet Oct 2013;161(10):2495–503. Epub 2013 Aug 15.

Namavar Y, Barth P, Kasher P, van Ruissen F, Brockmann K, Bernert G, Writzl K, Ventura K, Cheng EY, et al. Clinical, neuroradiological and genetic findings in pontocerebellar hypoplasia. Brain 2010;1:1–14.

Cheng EY, Hunt P, Naluai-Cecchini T, Fligner C, Fujimoto VY, Pasternack T, Schwartz J, Woodruff T, Cherry S, Hansen T, Vallente RU, Broman K, Hassold T: Cytogenetic studies of meiotic recombination in human females. PLoS Genet 2009 Sep;5(9):e1000661. Epub 2009 Sep 18.

Houmard B, Small C, Yang L, Naluai-Cecchini T, Cheng E, Hassold T, Griswold M: Global gene expression in the human fetal testis and ovary. Biol Reprod 2009 Aug;81(2):438–43.

Dighe M, Cheng E, Dubinsky T: Ultrasound manifestations of unusual trisomies, excluding trisomy 13, 18 and 21: a literature review. Ultrasound Q 2009 Mar;25(1):15–24.

Moskowitz SM, Chmiel JF, Stemen DL, Cheng E, Gibson RL, Marshall SG, Cutting GR: Clinical practice and genetic counseling for cystic fibrosis and CFTR-related disorders. Genetics in Medicine 2008;10(12):851–58.

Dighe M, Fligner C, Cheng E, Warren B, Dubinsky T: Fetal skeletal dysplasia: An approach to diagnosis with illustrative cases. Radiographics 2008;28(4):1061–77.

Vallente RU, Cheng EY, Hassold TJ. The synaptonemal complex and meiotic recombination in humans: New approaches to old questions (Review). Chromosoma 2006;115:241–249.

Cheng EY, Goss CH, McKone EF, Galic V, Debley CK, Tonelli MR, Aitken ML. Aggressive prenatal care results in successful fetal outcomes in CF women. J Cystic Fibrosis 2006;5:85–91.

Bennett R, Motulsky A, Bittles A, Hudgins L, Uhrich S, Locher-Doyle D, Sylvie K, Scott CR, Cheng E, McGilvray B, Steiner R, Olson D. Genetic counseling and screening of consanguineous couples and their offspring: Recommendations of the National Society of Genetic Counselors. J Genet Counseling 2002;11(2):97–119.

Cubert R, Cheng EY, Mack S, Pepin MG, Byers PH. Osteogenesis imperfecta: Mode of delivery and neonatal outcome. Obstet Gynecol 2001;97:66–69.

Cheng EY, Chen YJ, Disteche CM, Gartler SM. Analysis of a paracentric inversion in human occytes: Non-homologous pairing in pachytene. Hum Genet 1999;105:191–196.

Cheng EY, Chen YJ, Bonnet G, Gartler SM. An analysis of meiotic pairing in trisomy 21 oocytes using fluorescent in situ hybridization. Cytogenetics and Cell Genetics 1998;80:48–53.

Cheng EY, Chen YJ, Gartler SM. Chromosome painting analysis of early oogenesis in trisomy 18. Cytogenetics and Cell Genetics 1995;70:205–210.

Cheng EY, Gartler SM. A fluorescent in situ hybridization analysis of X chromosome pairing in human female meiosis. Hum Genet 1994;94:389–94.

Cheng EY, Luthy DA, Zebelman AM, Williams MA, Luthardt FW, Hickok DE, Lieppman RE, Coe SJ. A midtrimester screening test for fetal Down syndrome utilizing maternal serum alpha-fetoprotein, human chorionic gonadotropin and unconjugated estriol. Obstet Gynecol 1993;81:72–77.

Ashwood ER, Cheng EY, Luthy DA. Maternal serum alpha-fetoprotein and fetal trisomy 21 in women 35 years and older: Implications for alpha-fetoprotein screening programs. Am J Med Genet 1987;26(3):531–39.

Appointments & Practice Locations

Maternal and Infant Care Clinic (MICC)
UW Medical Center, 3rd Floor, SW 350
1959 NE Pacific St, Seattle, WA 98195

Appointments:   206.598.4070

 

Prenatal Diagnosis and Treatment Program
at Seattle Children's Hospital
Springbrook Professional Center
4540 Sand Point Way NE, Suite 320
Seattle, WA 98105

Appointments:   206.987.5629

 

UW Medicine Maternal Fetal Medicine Clinic
at Yakima Valley Memorial Hospital
3003 West Tieton Drive, Suite 240
Yakima, WA 98902

Appointments:   206.598.3900, or
                           855.464-6298 toll free