Goff Barbara

Barbara A Goff, MD

Professor and Chair, Department of Obstetrics and Gynecology
Adjunct Professor, Department of Medicine, Division of Surgery
Surgeon-in-Chief, University of Washington Medical Center

The Whole U - Faculty Friday Article: Barbara Goff

Joined UW Medicine:


Clinical Focus:

Gynecologic Oncology:
• Ovarian cancer and research on early detection
• Complex gynecologic oncology surgery
• Clinical trials for gynecologic malignancies
• Robotic surgery


Washington, 1992


• Obstetrics and Gynecology, 1994
• Gynecologic Oncology, 199


• MD Degree
   (University of Pennsylvania, 1986)
• Residency in Obstetrics and Gynecology
   (Brigham and Women's Hospital, 1990)
• Fellowship in Gynecologic Oncology
   (Massachusetts General Hospital, 1993)
• Certificate in Medical Management
   (University of Washington, 1999)

Research Interests:

• Screening and early detection of ovarian cancer
• Clinical trials for gynecologic malignancies
• Surgical interventions for gynecologic malignancies
• Surgical education

Current Research:

• OCRF Symptom Study


• American Congress of Obstetricians and Gynecologists
• Association of Professors of Gynecology and Obstetrics
• Gynecologic Oncology Group
• Puget Sound Oncology Consortium
• American Society of Clinical Oncology
• Society of Gynecologic Oncologists
• Western Association of Gynecologic Oncologists


• Gynecologic Cancer Foundation Public Service Award (2008)
• Ladies Home Journal, Medical Breakthrough Award
   for Early Detection of Ovarian Cancer (2007)
• America's Top Doctors for Cancer (2006)
• Seattle's Best Doctors (2010, 2007, 2006, 2003, 2002, 1998)
• Best Doctors in America Award (2005, 2001, 2000, 1999)
• Ovarian cancer National Alliance Rosaline Franklin Excellence in Research Award (2005)

Selected Publications:

McLean KA, Zhang W, Dunsmoor-Su RF, Shah CA, Gray HJ, Swensen RE, Goff BA. Pelvic exenteration in the age of modern chemoradiation. Gynecol Oncol 2011 Apr;121(1):131-4.

Thrall MM, Paley P, Pizer E, Garcia R, Goff BA. Patterns of spread and recurrence of sex cord-stromal tumors of the ovary. Gynecol Oncol 2011 Aug;122(2):242-5.

Goff BA, Matthews B, Andrilla CH, Miller JW, Trivers KF, Berry D, Lishner DM, Baldwin LM. How are symptoms of ovarian cancer managed: A Study of Primary Care Physicians. Cancer 2011 Mar 16 [Epub ahead of print].

Thrall MM, Goff BA, Symons RG, Flum DR, Gray HJ. Thirty-day mortality after primary cytoreductive surgery for advanced ovarian cancer in the elderly. Obstet Gynecol 2011 Sep;118(3):537-47.

Thrall MM, Gray HJ, Symons RG, Weiss NS, Flum DR, Goff BA. Trends in treatment of advanced epithelial ovarian cancer in the Medicare population. Gynecol Oncol 2011 Jul;122(1):100-6.

Press JZ, Allison KH, Garcia R, Everett EN, Pizer E, Swensen RE, Tamimi HK, Gray HJ, Goff BA. FOXP3+ regulatory T-cells are abundant in vulvar Paget's disease and are associated with recurrence. Gynecol Oncol 2011 Feb;120(2):296-9.

Gray HJ, Seifert E, Sal Y Rosas VG, Nicandri KF, Koh WJ, Goff BA. The abandoned radical hysterectomy for cervical cancer: clinical predictors and outcomes. Obstet Gynecol Intl 2010;2010743794.

Wurz K, Garcia RL, Goff BA, Mitchell PS, Lee JH, Tewari M, Swisher EM. MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma: Relationship to CDKN1B, CDKNIC and overall survival. Genes, Chromosomes Cancer 2010 Jul;49(7):577-84.

Devlin SM, Diehr PH, Andersen MR, Goff BA, Tyree PT, Lafferty WE. Identification of ovarian cancer symptoms in health insurance claims data. J Women's Health 2010 Mar;19(3):381-9.

McLean KA, Shah CA, Thompson SA, Gray HJ, Swensen RE, Goff BA. Ovarian cancer in the elderly: outcomes with neoadjuvant chemotherapy or primary cytoreduction. Gynecol Oncol 2010 Jul;118(1):43-6.

Gray HJ, Shah CA, Swensen RE, Tamimi HK, Goff BA. Alternative intraperitoneal chemotherapy regimens for optimally debulked ovarian cancer. Gynecol Oncol 2010 Mar;116(3):340-4.

Goff BA. Training and assessment in gynaecologic surgery: the role of simulation. Best Practice & Research Clinical Obstetrics & Gynaecology 2010 Dec;24(6):759-66.

Andersen MR, Goff BA, Lowe KA, Scholler N, Bergan L, Drescher CW, Paley P, Urban N. Use of a symptom index, CA125, and HE4 to predict ovarian cancer. Gynecol Oncol 2010 Mar;116(3):378-83.

Press JZ, Wurz K, Norquist BM, Lee MK, Pennil C, Garcia R, Welcsh P, Goff BA, Swisher EM. Identification of a preneoplastic gene expression profile in tubal epithelium of BRCA1 mutation carriers. Neoplasia 2010 Dec;12(12):993-1002.

Norquist BM, Garcia RL, Allison KH, Jokinen CH, Kernochan LE, Pizzi CC, Barrow BJ, Goff BA, Swisher EM. The molecular pathogenesis of hereditary ovarian carcinoma: alterations in the tubal epithelium of women with BRCA1 and BRCA2 mutations. Cancer 2010 Nov;116(22):5261-71.

Fialkow MF, Goff BA. Training the next generation of minimally invasive surgeons. J Minim Invasive Gynecol 2009 Mar-Apr;16(2):136-41.

Shah CA, Goff BA, Lowe K, Li CI. Factors affecting risk of mortality in women with vaginal cancer. Obstet Gynecol 2009 May;113(5):1038-45.

Swisher EM, Gonzalez RM, Taniguchi T, Garcia RL, Walsh T, Goff BA, Welsch P. Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas. Mol Cancer 2009;8:48.

Chisholm KM, Goff BA, Garcia R, King MC, Swisher EM. Genomic structure of chromosome 17 deletions in BRCA1-associated ovarian cancers. Cancer Genet Cytogenet 2008 May;183(1):41-8.

Shah CA, Allison KH, Garcia RL, Gray HJ, Goff BA, Swisher EM. Intratumoral T cells, tumor-associated macrophages, and regulatory T cells: association with p53 mutations, circulating tumor DNA and survival in women with ovarian cancer. Gynecol Oncol 2008 May;109(2):215-9.

Fox KV, Shah CA, Swisher EM, Garcia RL, Mandel LS, Gray HJ, Swensen RE, Goff BA. An evaluation of cervical cancer in women age sixty and over. Gynecol Oncol 2008 Apr;109(1):53-8.

Goff BA, Holmberg LA, Veljovich D, Kurland BF. Treatment of recurrent or persistent platinum-refractory ovarian, fallopian tube or primary peritoneal cancer with gemcitabine and topotecan: a phase II trial of the Puget Sound Oncology Consortium. Gynecol Oncol 2008 Aug;110(2):146-51.

Goff BA. Quality measures in gynecologic cancers: what and when? Gynecol Oncol 2008 Jul;110(1):3-4.

Goff BA. Surgical education: what role should gynecologic oncologists play? Gynecol Oncol 2008 May;109(2):164-5.

Goff BA. Changing the paradigm in surgical education. Obstet Gynecol 2008 Aug;112(2 Pt 1):328-32.

Goff BA, VanBlaricom A, Mandel L, Chinn M, Nielsen P. Comparison of objective, structured assessment of technical skills with a virtual reality hysteroscopy trainer and standard latex hysteroscopy model. J Repro Med 2007 May;52(5)407-12.

Appointments & Practice Locations

UW Medical Center 8SE Oncology
Cascade Tower, 8th floor
1959 NE Pacific Street
Seattle, WA 98195

Appointments:   206.598.8300