Pennington Kathryn Dept web

Kathryn P Pennington, MD

Assistant Professor

Joined UW Medicine:


Clinical Focus:

• Complex gynecologic oncology surgery
• Minimally invasive surgery
• Treatment of gynecologic cancers


Washington, 2011


• Obstetrics and Gynecology, 2011
• Gynecologic Oncology, 2018


• MD Degree
   (University of Michigan Medical School, 2006)
• Residency in Obstetrics and Gynecology
   (University of Michigan, 2010)
• Fellowship in Gynecologic Oncology
   (University of Washington, 2015)

Research Interests:

• Gynecologic cancer survivorship
• Clinical trials for gynecologic malignancies
• Molecular genetics of sporadic and familial ovarian cancer


• Alpha Omega Alpha
• Society of Gynecologic Oncologists
• American College of Obstertricians and Gynecologists

Selected Publications:

Pennington KP, Walsh T, Harrell MI, Lee MK, Pennil CC, Rendi MH, Thornton A, Norquist BM, Casadei S, Nord AS, Agnew KJ, Pritchard CC, Scroggins S, Garcia RL, King MC, Swisher EM. Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas. Clin Cancer Res 2014; 20(3):764-75.

Pennington KP, Wickramanayake A, Norquist BM, Pennil CC, Garcia RL, Agnew KJ, Taniguchi T, Welcsch P, Swisher EM. 53BP1 expression in sporadic and inherited ovarian carcinoma: relationship to genetic status and clinical outcomes. Gynecol Oncol 2013; 128(3):439-9.

Norquist BM, Pennington KP, Agnew KJ, Harrell MI, Pennil CC, Lee MK, Casadei S, Thornton AM, Garcia RL, Walsh T, Swisher EM. Characteristics of women with ovarian carcinoma who have BRCA1 and BRCA2 mutations not identified by clinical testing. Gynecol Oncol 2013;128(3):483-7.

Pennington KP, Walsh T, Lee M, Pennil C, Novetsky AP, Agnew KJ, Thornton A, Garcia R, Mutch D, King MC, Goodfellow P, Swisher EM. BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma. Cancer 2013;119(2):332-8.

Pennington KP, Swisher EM. Hereditary ovarian cancer: beyond the usual suspects. Gynecol Oncol 2012;124(2):347-53.

Walsh T, Casadei S, Lee MK, Pennil CC, Nord AS, Thornton AM, Roeb W, Agnew KJ, Stray SM, Wickramanayake A, Norquist B, Pennington KP, Garcia RL, King MC, Swisher EM. Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc Natl Acad Sci USA 2011;108(44):18032-7.

Berent-Spillson A, Love T, Pop-Busui R, Sowers M, Persad CC, Pennington KP, Eyvazaddeh AD, Padmanabhan V, Zubieta JK, Smith YR. Insulin resistance influences central opioid activity in polycystic ovary syndrome. Fertility and Sterility [accepted for publication 3/2011].

Pennington KP, Pulaski H, Pennington M, Liu JR. Too much of a good thing: suicide prevention promotes chemoresistance in ovarian carcinoma. Current Cancer Drug Targets 2010;10(6):575-83.Review

Eyvazzadeh AD, Pennington KP, Pop-Busui R, Sowers M, Zubieta JK, Smith YR. The Role of the endogenous opioid syndrome. Fertil Steril 2009;92(1):1-12.

Boggs K, Duren P. Zeroes of Hypergeometric Functions. Computational Methods and Function Theory Volume
1 (2001), No. 1, 275-287.

Appointments & Practice Locations

UW Medical Center 8SE Oncology
Cascade Tower, 8th floor
1959 NE Pacific Street
Seattle, WA 98195

Appointments:   206.598.8300