Gravett Michael Dept web

Michael G Gravett, MD

Professor, Department of Obstetrics and Gynecology
Adjunct Professor, Department of Global Health

Joined UW Medicine:


Clinical Focus:

Maternal-Fetal Medicine:
• Perinatal infectious disease
• Prematurity prevention


• Washington, 1978
• Oregon, 1990


• Obstetrics and Gynecology, 1985
• Maternal-Fetal Medicine, 1987


• MD Degree
   (University of California, Los Angeles, 1977)
• Residency in Obstetrics and Gynecology
   (University of Washington, 1981)
• Senior Fellow, Infectious Disease, Immunology
   (University of Washington, 1981–82)
• Senior Fellow, Maternal-Fetal Medicine
   (University of Washington, 1982–83)

Research Interests:

• Ob/Gyn infectious diseases
• Causes/prevention of prematurity
• Global health
• Maternal/fetal immunology
• Proteomics

Current Research:

• International Fetal and Newborn Growth Standards for the 21st Century
• The Infant Development and Environment Study (TIDES)
• Preventing Preterm Birth: An Initiative of Family Health Grand Challenges
   in Global Health


• American Society for Microbiology
• Society for Maternal-Fetal Medicine
• Pacific Coast Obstetrical and Gynecological Society
• Society for Gynecologic Investigation
• Perinatal Research Society
• Infectious Disease Society for Obstetrics and Gynecology (past-President)


• Seattle Top Doctors 2010
• President's Plenary Award, Society for Gynecologic Investigators, 2007
• Dru Carlson Memorial Award for Best Research in Ultrasound and Genetics, Society for Maternal-Fetal Medicine, 2005
• Best Plenary Abstract Award, Society for Maternal-Fetal Medicine, 2004

Selected Publications:

Simmons LE, Rubens CE, Gravett MG. Preventing preterm birth and neonatal mortality: exploring the epidemiology, causes, and interventions. Semin Perinatol 2010;34:408-415.

Gravett MG, Rubens C, Nunes T, and the GAPPS Review Group. Global report on preterm birth and stillbirth (2 of 7): the role of discovery science. BMC Pregnancy and Childbirth 2010; 10(Supp; 1):S2

Gravett MG, Adams KM, Sadowsky DW, Grosvenor AR, Witkin SS, Axthelm MK, Novy MJ. Immunomodulators plus antibiotics delay preterm delivery after experimental intra-amniotic infection in a nonhuman primate model. Am J Obstet Gynecol. 2007;197:518.e1-518.e8.

Gravett MG, Novy MJ, Thomas A, Schneider KA, Reddy AP, Dasari S, Jacob T, Lu X, Rodland M, Pereira L, Sadowsky DW, Roberts CT, Nagalla SR. Proteomic analysis of cervical-vaginal fluid: identification of novel biomarkers for detection of intra-amniotic infection. J Proteome Res 2007;6:89-96.

Gravett MG, Novy MJ, Rosenfeld RG, Reddy AP, Haung J, Jacob T, Turner M, McCormack A, Lapidus JA, Hitti J, Eschenbach DA, Roberts CT, Nagalla SR. Diagnosis of intraamniotic infection by proteomic profiling and identification of novel biomarkers. JAMA 2004;292:462–469.

Sadowsky DW, Novy MJ, Witkin SS, Gravett MG. Dexamethasone or interleukin-10 blocks interleukin-1ß induced uterine contractions in pregnant rhesus monkeys. Am J Obstet Gynecol 2003;188:252–263.

Gravett MG, Hitti J, Hess DL, Eschenbach DA. Intrauterine infection and preterm delivery: evidence for activation of the fetal hypothalamic-pituitary-adrenal axis. Am J Obstet Gynecol 2000;182:1404–1413.

Gravett MG, Witkin SS, Haluska GJ, Edwards JL, Cook MJ, Novy MJ. An experimental model for intra-amniotic infection and preterm labor in rhesus monkeys. Am J Obstet Gynecol 1994;171:1660–1667.

Gravett MG, Nelson HP, DeRouen T, et al. Independent association of bacterial vaginosis and Chlamydia trachomatis infection with adverse pregnancy outcome. JAMA 1986;256:1899–1903.

Gravett MG, Eschenbach DA, Hummel D, et al. Preterm labor associated with subclinical amniotic fluid infection and with bacterial vaginosis. Obstet & Gynecol 1985;67:229–237.