Reproductive Endocrinology and Infertility

Study of Women's Health Across the Nation (SWAN)

Genevieve S. Neal-Perry, MD, PhD

The project includes training of clinic staff to instruct women regarding the collection of samples, consultation with staff, interpretation of the data, and writing of manuscripts. Information learned from the proposed studies will be presented in venues that target clinical audiences for those who provide medical care for menopausal and perimenopausal women.

Funding Source: Albert Einstein College of Medicine of Yeshiva University
End Date: 6-30-17

 

Identifying mechanisms of age-related diminished ovarian function with epigenomic approaches

Bo Yu, MD, MS

The main goal of my RSDP project is to elucidate the epigenetic mechanisms underlying age-related decline in ovarian function and female fertility, by identifying epigenetic changes associated with diminished ovarian function in human oocytes and granulosa cells, and by examining the role of oxidative stress in inducing these epigenetic changes. In the long term, findings from this project may lead to development of: i) prevention strategies in delaying ovarian aging process, ii) epigenetic tests in predicting reproductive life span, and iii) treatment options in accelerating oocyte in vitro maturation.

Funding Source: Albert Einstein College of Medicine of Yeshiva University
End Date: 6-30-17