Shailender Bhatia, MD

Shailender Bhatia, MD

Associate Professor
Department of Medicine
Division of Oncology

Mailing Address

Seattle Cancer Care Alliance
825 Eastlake Ave W, CE2-128
Seattle, WA 98109-1023

Admin Contact

Samantha Lepidi

Specialty / Expertise

  • Skin Cancers (Melanoma, Merkel Cell Cancer)
  • Kidney Cancers
  • Immunotherapy
  • Intra-tumoral therapy
  • Targeted therapy

Research Interests

Dr. Bhatia’s research efforts are mostly focused on clinical trials that aim at improving outcomes in skin cancers (especially Melanoma and Merkel cell carcinoma) and Kidney cancers. He is especially interested in those novel therapeutic approaches that stimulate the immune system against cancer and those that target therapy to the tumors in order to spare unnecessary toxicity.

Current Research Projects

A pharmacodynamic study of intratumoral injection of Glucopyranosyl Lipid A (GLA), a Toll-like receptor 4 (TLR4) agonist, in patients with Merkel Cell Carcinoma

A Multicenter Phase II Trial of intratumoral pIL-12 electroporation in advanced stage cutaneous and in transit malignant melanoma

A Phase I Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Immunoregulatory Activity, and Preliminary Antitumor Activity of BMS-982470 (Recombinant Interleukin 21, rIL-21) in combination with Ipilimumab in Subjects with Unresectable Stage III or Stage IV Melanoma

A Phase II study of intratumoral injection of Interleukin-12 plasmid and in vivo electroporation in patients with Merkel Cell Cancer An Exploratory Study of the Biologic Effects of BMS-936558 (Anti-PD-1 Monoclonal Antibody) Treatment in Subjects with Advanced Melanoma (Unresectable or Metastatic)


Dr. Bhatia received his MBBS (equivalent to MD) degree at the All India Institute of Medical Sciences (AIIMS) in New Delhi, INDIA and completed his Internal Medicine Internship and Residency at the University of Connecticut Health Center, Farmington, CT. He completed his Post-Doctoral fellowship in Hematology/Oncology at the University of Washington/Fred Hutchinson Cancer Research Center, Seattle, WA.

Selected Publications

Bhatia S, Tykodi SS, Thompson JA. Treatment of Metastatic Melanoma: an overview. Oncology (Williston Park). 2009 May; 23(6):488-96.

Bhatia S, Huber BR, Upton MP, Thompson JA. Inflammatory enteric neuropathy with severe constipation after ipilimumab treatment for melanoma: a case report. J Immunother. 2009 Feb-Mar;32(2):203-5.

Bhatia S, Thompson JA. Temsirolimus in patients with advanced renal cell carcinoma: an overview. Adv Ther. 2009 Jan;26(1):55-67. Epub 2009 Jan 26.

Thompson JA, Curti BC, Redman BG, Bhatia S, Weber JS, Agarwala SS, Sievers EL, Hughes SD, DeVries TA, Hausman DF. Phase I study of recombinant interleukin-21 in patients with metastatic melanoma and renal cell carcinoma. J Clin Oncol. 2008 Apr 20;26(12):2034-9. Epub 2008 Mar 17.

Bhatia S, Bauer F, Bilgrami SA. Candidiasis-associated hemophagocytic lymphohistiocytosis in a patient infected with human immunodeficiency virus. Clin Infect Dis. 2003 Dec 1;37(11):e161-6. Epub 2003 Nov 6.

Last updated: October 2018