Faculty

Edward N. Libby MD

Edward N. Libby MD

Associate Professor
Department of Medicine
Division of Oncology
University of Washington
Associate Member
Clinical Research Division
Fred Hutchinson Cancer Research Center

Mailing Address

Seattle Cancer Care Alliance
825 Eastlake Ave E, G3-200
Seattle, WA 98109-1023

Admin Contact

Gabriel Lungstrom
206-606-7031
glun1223@seattlecca.org

Specialty / Expertise

  • Multiple myeloma
  • Plasma cell leukemia
  • Amyloidosis
  • Waldenstrom’s macroglobulinemia
  • Plasmacytoma
  • POEMS Syndrome
  • MGUS and smoldering multiple myeloma

Research Interests

Multiple Myeloma
Amyloidosis
Waldenstrom's macroglobulinemia

Current Research Projects

AFT-29 / MMY2004. The GRIFFEN study. A randomized, phase II study of lenalidomide, bortezomib and dexamethasone with or without Daratumumab as pre-induction for autologous stem cell transplantation. ClinicalTrials.gov Identifier: NCT00874742

A Safety and Efficacy Study of Carfilzomib and Pomalidomide With Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma ClinicalTrials.gov Identifier: NCT01464034

A Phase I Open-label, Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Clinical Activity of the Antibody Drug Conjugate GSK2857916 in Subjects with Relapsed/Refractory Multiple Myeloma and Other Advanced Hematologic Malignancies Expressing BCMA ClinicalTrials.gov Identifier: NCT02064387

A Phase 3, Randomized, Open-Label, Multicenter Study Comparing the Efficacy and Safety of the Bruton’s Tyrosine Kinase (BTK) Inhibitors BGB-3111 and Ibrutinib in Subjects with Waldenström’s Macroglobulinemia.ClinicalTrials.gov Identifier: NCT03053440

Training

Dr. Libby received his B.S. from the University of Texas at El Paso and his M.D. from the University of Texas Health Science Center at Houston. He completed his Internal Medicine residency at the University of New Mexico(UNM) in Albuquerque. He was a Fellow in Hematology at UNM and at UNC Chapel Hill.

Selected Publications

Andrew J. Cowan, Zandra K. Klippel, Philip A. Stevenson, Teresa S. Hyun, Sherilyn Tuazon, Pamela S. Becker, Damian J. Green, Leona A. Holmberg, David G. Coffey, Ajay K. Gopal, Edward N. Libby. Pre-Transplantation Novel Agent Induction Predicts Progression-Free Survival for Patients with Immunoglobulin Light-Chain Amyloidosis Undergoing High-Dose Melphalan and Autologous Stem-Cell Transplantation. Amyloid. 2016 Dec; 23(4): 254-259. PMID: 27879147.

Libby EN, Becker PS, Burwick N, Green DJ, Holmberg L, Bensinger WI. Panobinostat: A Review of Trial Results and Future Prospects in Multiple Myeloma. Expert Rev Hematol. 2015 Feb; 8(1)9-18. PMID: 25410127.

Mikhael JR, Reeder CB, Libby EN, Costa LJ, Bergsagel PL, Buadi F, Mayo A, Nagi Reddy SK, Gano K, Dueck AC, Stewart AK.Phase Ib/II Trial of CYKLONE (Cyclophosphamide, Carfilzomib, Thalidomide and Dexamethasone) for Newly Diagnosed Myeloma.Br J Haematol. 2015 Apr; 169(2):219-27. PMID: 25683772.

Phipps C, Linenberger M, Holmberg LA, Green D, Becker P, Connelly-Smith L, Klippel Z, Burwick N, Gopal A, Bensinger WI,Libby E . Utilization of Stored Autologous PBSCs to Support Second Autologous Transplantation in Multiple Myeloma Patients in the Era of Novel Agent Therapy. Bone Marrow Transplant. 2015 May; 50(5):663-7. PMID: 25730190.

Libby E, Garcia D, Quintana D, Fekrazad MH, Bauman J, Ebaid A, Hromas R, Rabinowitz I, Wiggins C. Disease-Specific Survival for Patients with Multiple Myeloma: Significant Improvements Over Time in All Age Groups. Leuk Lymphoma. 2014 Dec; 55(12):2850-7. PMID: 24588734.

Libby EN. Diagnosis and treatment of follicular lymphoma: where do we stand? Int. J. Hematol. Oncol. 2012. 1(2), 169–178.

Garcia D, Libby E, Crowther M. The Novel Anticoagulants. Blood 2010 Jan 7;115(1):15-20.

Garcia D, Highfill J, Finnerty K, Varoz E, McConkey S, Hutchinson K,Libby E. A prospective controlled trial of a pharmacy-driven alert system to increase thromboprophylaxis rates in medical inpatients. Blood Coagul Fibrinolysis. 2009 Oct;20(7):541-5.

Oertel LB, Libby EN. Is patient self-testing a good thing? J Thromb Thrombolysis. 2010 Feb;29(2):214-8.

Wray J, Williamson E, Sheema S, Lee s, Libby E, Willman C, Nickoloff J, Hromas R. Metnase Mediates Chromosome Decatenation in Acute Leukemia Cells. Blood.2009 Aug 27;114(9):1852-8.

Garcia D, Highfill J, Finnerty K, Varoz E, McConkey S, Hutchinson K, Libby E. A prospective controlled trial of a pharmacy-driven alert system to increase thromboprophylaxis rates in medical inpatients. Blood Coagul Fibrinolysis. 2009 Oct;20(7):541-5.

Libby E. Pregnancy and Thromboembolic Disease. Thromb Res.2008;123 Suppl 1:S55-7.

Libby E, Booker J,Gulley M, Garcia D, Moll S. False Negative Factor V Leiden Genetic Testing in a Patient with Recurrent Deep Venous Thrombosis. Am J. Hem 81:284-289,2006.

Garcia D, Ageno W, Libby E. Pulmonary Embolism A Review of Current Trends in Evaluation and Treatment. Br J Haematol 2005 Nov;131(3):301-12.

Libby E, White G. Intracranial Pseudotumor in Haemophilia. Haemophilia 2004;10:186-188. Libby E. Garcia D. A Survey of Vitamin K Use by Anticoagulation Clinics. Archives of Internal Medicine, 2002; 162(16): 1893-1896.

Libby E. Garcia D. A Survey of Vitamin K Use by Anticoagulation Clinics. Archives of Internal Medicine, 2002; 162(16): 1893-1896.

Last updated: August 2017

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