Specialty / Expertise

Breast Cancer

Research Interests

Clinic practice in breast and hematologic malignancy and  hematopoietic transplantation
Immunogenetics of and immunotherapy for solid tumors (breast)
Cell-based therapy for immunologic tolerance in hematopoietic and solid organ transplantation
Non-invasive surrogate biomarkers for transplant rejection and cancer detection

Current Research Projects

Research Staff

Training

Dr. Gadi received his MD and PhD from the University of Alabama School of Medicine at Birmingham, Birmingham, AL. He completed his Internal Medicine Residency at the University of Washington, Seattle, WA. He was a Post-Doctoral Fellow in Oncology at the University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA.

Selected Publications:

Gadi VK, Malone KE, Guthrie KA, Porter PL, Nelson JL. Case-control study of fetal microchimerism and breast cancer. PLoS ONE 2008 3(3):e1706.

Gadi VK. Chronic lymphocytic lymphoma: another example of parental favoritism. Leuk Lymphoma 2007 48(12):2306-2307.

Gadi VK and Nelson JL. Fetal microchimerism in breast cancer. Cancer Res 2007 67(19):9035-9038.

Gadi VK, Nelson JL, Boespflug ND, Guthrie KA, Kuhr CS. Donor DNA concentration in recipient serum correlate with pancreas-kidney rejection. Clin Chem. 2006 Mar;52(3):379-82.

Bharara, S, Sorscher EJ, Gillespie GY, Lindsey JR, Hong JS, Curlee KV, Allan PW, Gadi VK, Alexander SA, Secrist JA, Parker WB, Waud WR. Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus based glioma therapy. Hum Gene Ther. 2005 Mar;16(3):339-47.

Gadi VK, Alexander SD, Parker WB, Allan PW, Jr, Waud WR, Sorscher EJ. A long acting suicide gene toxin, 6-methyl purine, inhibits slow growing tumors after a single administration. J Pharmacol Exp Ther. 2003 Mar;304(3):1280-4.

Gadi VK, Alexander SD, Kudlow JE, Allan P, Parker WB, Sorscher EJ. In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells. Gene Ther. 2000 Oct;7(20):1738-43.