Specialty / Expertise

Genitourinary Cancer

Research Interests

Epidermal growth factor receptor family oncogenesis
Peptide vaccine to EGFRvIII
Mechanisms of drug resistance to taxanes
Prostate cancer

Current Research Projects

Research Staff

Training

Dr. Montgomery received his MD from Duke University, Durham, NC. He completed his Internal Medicine Residency at Brigham and Women's Hospital, Boston, MA. He was a Post-Doctoral Fellow in Hematology/Oncology at the University of Washington/Fred Hutchinson Cancer Research Center, Seattle, WA.

Selected Publications:

Plymate SR, Haugk K, Coleman I, Woodke L, Vessella R, Nelson P, Montgomery RB, Ludwig DL, Wu JD. An antibody targeting the type I insulin-like growth factor receptor enhances the castration-induced response in androgen-dependent prostate cancer. Clin Cancer Res 2007 13(21):6429-6439.

Montgomery RB, Goldman B, Tangen CM, Hussain M, Petrylak DP, Page S, Klein EA, Crawford ED; Southwest Oncology Group. Association of body mass index with response and survival in men with metastatic prostate cancer: Southwest Oncology Group trials 8894 and 9916. J Urol 2007 178(5):1946-1951; discussion 1951.

Montgomery RB, Nelson PS, Lin D, Ryan CW, Garzotto M, Beer TM. Diethylstilbestrol and docetaxel: a Phase II study of tubulin active agents in patients with metastatic, androgen-independent prostate cancer. Cancer 2007 110(5):996-1002.

Mostaghel EA, Montgomery RB, Lin DW. The basic biochemistry and molecular events of hormone therapy, Curr Urol Rep, 2007 8(3):224-232

Wu JD, Haugk K, Coleman I Woodke L, Vessella R, Nelson P, Montgomery RB Ludwig DL, Plymate SR. Combined in vivo effect of A12, a type 1 insulin-like growth factor receptor antibody, and docetaxel against prostate cancer tumors. Clin Cancer Res 2006 12(20 Pt1):6153-6160

Wright JL, Lin DW, Dewan P, Montgomery RB. Tumor lysis syndrome in a patient with metastatic, androgen independent prostate cancer. Int J Urol 2005 12(11):1012-1013

Montgomery RB, Bonham M, Nelson PS, Grim J, Makary E, Vessella R, Stahl WL. Estrogen effects on tubulin expression and taxane mediated cytotoxicity in prostate cancer cells. Prostate 2005 65(2):141-150