Specialty / Expertise

Genitourinary Cancer

Research Interests

The focus of current work in the Nelson lab involves efforts to understand the process of prostate carcinogenesis with an aim toward developing diagnostic, prognostic, and therapeutic strategies.

Current Research Projects

Research Staff

Training

Dr. Nelson received his MD from the University of Kansas, Lawrence, KS. He completed his Internal Medicine Residency at the University of Kansas, Lawrence, KS. He was a Post-Doctoral Fellow in Hematology/Oncology at the University of Washington/Fred Hutchinson Cancer Research Center, Seattle, WA.

Selected Publications:

Marks LS, Mazer NA, Mostaghel E, Hess DL, Dorey FJ, Epstein JL, Veltri RW, Makarov DV, Partin AW, Bostwick DG, Macairan ML, Nelson PS. Effect of testosterone replacement therapy on a prostate tissue in men with late-onset hypgonadism: a randomized controlled trial. JAMA. 2006 Nov 15;296(19):2351-2361.

Coleman IM, Kiefer JA, Brown LG, Pitts TE, Nelson PS, Brubaker KD, Vessella RL, Corey E. Inhibition of androgen independent prostate cancer by estogenic compounds is associated with increased expression of immune-related genes. Neoplasia. 2006 Oct;8(10):862-878.

Lin DW, Nelson PS. Microarray analysis and tumor classification. N Engl J Med. 2006 Aug 31;355(9):960; author reply 960.

Page ST, Lin DW, Mostaghel EA, Hess DL, True LD, Amory JK, Nelson PS, Matsumoto AM, Bremner WJ. Presistent intrapostatic androgen concentrations after medical castration in healthy men. J Clin Endcrinol Metab. 2006 Oct;91(10):3850-3856.

True L, Coleman I, Hawley S, Huang CY, Gifford D, Coleman R, Beer TM, Gelmann E, Datta M, Mostaghel E, Knudsen B, Lange P, Vessella R, Lin D, Hood L, Nelson PS. A molecular correlate to the Gleason grading system for prostate adenocarcinoma. Proc Natl acad Sci U S A. 2006 Jul 18;103(29):10991-10996.

Lin DW, Coleman IM, Hawley S, Dumpit R, Gifford D, Kezele P, Hung H, Knudsen BS, Kristal AR, Nelson PS. Influence of surgical manipulation on prostate gene expression: implications for molecular correlates of treatment effects and disease prognosis. J Clin Oncol. 2006 Aug 10;24(23):3763-3770.